Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

physiology-Blood Module > lec 10: Functions of WBCs > Flashcards

lec 10: Functions of WBCs Flashcards

1
Q

White blood cells are

A

large, nucleated, motile cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Total leukocytic count range is between………….

A

4000-11000 WBC /mm³

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Neutrophils

A

(60-70%).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Eosinophils

A

(1-4%).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Basophils

A

(0.25-0.5% )

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Lymphocytes

A

(25-33 %).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Monocytes

A

(2-6%).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

It is the movement of leukocytes which starts by protrusion of
pseudopodium from one end, then movement of the remainder of
the cell towards this pseudopodium.

A

Ameboid motion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Chemotaxis

A

A. Some of the bacterial or viral toxins.
B. Degenerative products of the inflamed tissues.
C. Leukotrienes and polypeptides from WBCs (lymphocytes,
mast cells and basophils).
D. Several components of the “complement complex (C5a).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Diapedesis, amoeboid movement, chemotaxis and phagocytosis are evident in …………………and……………

A

NEUTROPHILS and MONOCYTES.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Opsonization: It is the coating of the foreigner

(bacteria) by opsonins like

A

IGg , C3b

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

……………from neutrophils protrude around the bacteria and fuse to form a phagosome

A

Pseudopodia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

the most numerous white blood cell in the circulation

A

Neutrophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

increase in infection with pyogenic bacteria.

A

Neutrophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Average half life of the inactivated neutrophil in the circulation is

A

6 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

A single neutrophil can usually phagocytize ……………….. before the neutrophil itself becomes inactivated and dies

A

3 to 20 bacteria

17
Q

neutrophil can synthesize toxic oxygen metabolites like …………………………………………..

A

superoxide radical (O‾₂) and hydrogen peroxide (H₂O₂) and hypochlorous acid (HOCl).

18
Q

……………….exhibit diapedesis , chemotaxis and weak phagocytosis

A

Mature eosinophils

19
Q

the least common of granulocytes in peripheral blood

A

Basophils

20
Q

do not exhibit phagocytosis

A

Basophils

21
Q

They bear membrane receptors to IgE and are involved in allergic reactions

A

Basophils

22
Q

……………….. increase in parasitic and allergic conditions

A

Eosinophils

23
Q

functions of Basophils

A
  • Release of HISTAMINE and other inflammatory mediators when activated . These mediators initiate INFLAMMATION
  • Release of HEPARIN which prevents blood coagulation by acting as a cofactor for anti-thrombin III. Heparin may also exert anti-inflammatory effects
24
Q

Basophils are involved in…………………….which range from mild urticaria to severe anaphylactic shock.

A

type- I HYPERSENSITIVITY

25
Q 
Ig E (the antibody that causes allergic reactions) become attached to basophlis and mast cells. Binding of IgE with its specific allergen→ to rupture of cytoplasmic granules of MAST CELLS and BASOPHILS with subsequent release of HEPARIN and ALLERGIC
MEDIATORS which include:
A
  1. Histamine
  2. SRSA (Slow reacting substance of anaphylaxis), known now as LEUKOTRIENES
  3. bradykinin
  4. Lysosomal enzymes
  5. Serotonin.
26
Q

the largest blood cells

A

Monocytes

27
Q

Its cytoplasm is rich in lysosomes and they are professional phagocytic cells.

A

Monocytes

28
Q

They circulate in the blood for 72 hours then migrate to the tissues where they change into tissue macrophages (large phagocytic cells), whose life span is unknown

A

Monocytes

29
Q

Tissue macrophages constitute the tissue macrophage system (Reticulo-endothelial
system) which include :-

A
  1. Kupffer cells in the liver.
  2. Pulmonary alveolar macrophages (PAM).
  3. Microglia in the brain.
  4. Bone osteoclasts.
30
Q

………………………….form the core of immune system in humans. They provide defense against targets to which they are programmed

A

Lymphocytes

31
Q

About………………………of body lymphocytes are found in the peripheral blood and the rest are in the lymphoid tissues.

A

2%

32
Q

…………………..are responsible for humoral immunity. , produces immunoglobulins .

A

B-lymphocytes

33
Q

……………….. are responsible for cell mediated immunity . They attack and kill virus- infected cells as
well as malignant cells . They also facilitate antibody
production by B-cells.

A

T-lymphocytes

34
Q

WBCs are activated by …………………………..

A

contact with the organism or its toxin.

35
Q

• Activated WBCs show …………………………

A

increased motor activity, phagocytosis and degranulation.

36
Q

The…………….. is stimulated by different cytokines to increase leukopoiesis.

A

bone marrow

37
Q

• Once the organism is eradicated, Immune cells undergo apoptosis except for………………

A

memory cells.

38
Q

prevent overactivity of the immune system

A

T-regulatory cells

physiology-Blood Module (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions