LEC 3: Cardiovascular Disease

Question 1

What are the three types of cardiovascular disease?

Answer 1

1. Atherosclerosis
2. Coronary Artery Disease (CAD)
3. Acute Coronary Syndrome (ACS)

Question 2

What is the most common cause for cardiovascular disease?

Answer 2

Coronary atherosclerosis

Question 3

Coronary Atherosclerosis

Answer 3

A buildup of plaque inside the artery walls. This buildup causes the inside of the arteries to become narrower and slows down the flow of blood.

Question 4

What is the etoilogy and pathophysiology for cardiovascular disease ?

Answer 4

• Characterized by fat and lipid deposits in the inner lining or artery that obstruct circulation
• When vessel walls damaged, platelets activated and aggregate
• Thrombin generated, fibrin formed
• Results in occlusion, reduced blood flow, MI, or death

Question 5

What are the three stages of development for atherosclerosis?

Answer 5

1. Fatty streak
2. Raised fibrous plaque
3. Complicated lesion

Question 6

Stages of Development: Fatty Streak

Answer 6

Lipid filled smooth muscle cells migrate to injured vessel area

Question 7

Stages of Development: Raised Fibrous Plaque

Answer 7

• More lipid and smooth muscle adheres to damaged wall

- Lesion build up

Question 8

Stages of Development: Complicated Lesion

Answer 8

• Platelets accumulate; thrombus formation
• Most dangerous
• Thrombus grows
• Continued narrowing or occlusion