Lec 11 Review Flashcards

1
Q

Calabar bean:

  • Scientific name
  • Part used
  • Bioactive compound
A
  • Physostigma venenosum
  • Bean
  • Physostigmine (indole alkaloid)
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2
Q

Deadly Nightshade:

  • Scientific name
  • Part used
  • Bioactive compound
A
  • Atropa belladonna
  • Foliage and berries
  • Atropine (tropane alkaloid)
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3
Q

T or F: Atropine is a muscarinic cholinergic blocking agent

A

T

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4
Q

Castor bean:

  • Scientific name
  • Part used
  • Bioactive compound
A
  • Ricinus communis
  • Bean
  • Ricin (glycoprotein)
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5
Q

T or F: Ricin is a Ribosome inactivating protein

A

T

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6
Q

Rosary pea:

  • Scientific name
  • Part used
  • Bioactive compound
A
  • Abrus precatorius
  • Bean
  • Abrin
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7
Q

Name the 2 major forms of lectin:

A
  • Prolamine

- Agglutinin

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8
Q

Toxic lectins that serve as a storage proteins:

A

prolamine ex: gluten

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9
Q

Class of lectins that induce the clumping of red blood cells:

A

agglutinin, wheat germ agglutinin, ricin

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10
Q

WGA bind to _________________ and causes tight junctions to open

A

epidermal growth factor

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11
Q

WGA binds to 2 sugars found on cell membrane:

A
  • N-acetylglucosamine

- N-acetylneuraminic

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12
Q

Curare:

  • Scientific name
  • Part used
  • Bioactive compound
A
  • Chondrodendron tomentosum
  • Bark/woody stems
  • tubocurarine (alkaloid)
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13
Q

Tubocurarine blocks the ________________ at the neuromuscular junction

A

nAchR

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14
Q

The antidote for curare poisoning is an __________________ such as physostigmine

A

acetylcholinesterase inhibitor

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15
Q

Foxglove:

  • Scientific name
  • Part used
  • Bioactive compound
A
  • Digitalis purpurea
  • leaves
  • Digoxin (cardiac glycoside)
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16
Q

Digoxin inhibits the the Na/K ATPase in the myocardium. The inhibition causes a decrease in ______________

A

heart rate and increase in stroke volume

17
Q

Wolf’s bane:

  • Scientific name
  • Part used
  • Bioactive compound
A
  • Aconitum spp.
  • All parts Roots/tubers esp
  • Aconite (alkaloid)