LEC 10: Biomolecules Flashcards
most important elements in living matter; elements of life
CHNOPS
elements of life composes ____ % of humans
97.9%
elements of life by body mass
- carbon = 18%
- hydrogen = 10%
- oxygen = 65%
- nitrogen = 3%
4 biomolecules
- proteins
- carbohydrates
- lipids
- nucleic acids
polymeric substances composed of many amino acids linked together in a unique sequence
proteins
classifications of proteins
- simple
- conjugated
yield only amino acids when hydrolyzed
simple proteins
yield amino acids plus other products
conjugated proteins
building blocks of proteins
amino acids
what do amino acids do
- break down food
- grow and repair body tissue
- make hormones and brain chemicals
- provide an energy source
- maintain healthy skin, hair and nails
- build muscle
- boost your immune system
- sustain a normal digestive system
amino acid is any molecule with at least one ____ and one _____
- carboxyl group
- amino group
amino acids that are required to maintain good health; cannot be synthesized in the body and must be supplied from dietary protein
essential amino acids
either complete or incomplete based on the presence or absence of the 10 essential amino acids
dietary protein
supplies all the essential amino acids
complete protein
deficient in one or more essential amino acids
incomplete protein
good sources of complete proteins
animal based foods
sources of incomplete proteins
plant based foods
macromolecule composed of carbon, hydrogen, and oxygen
carbohydrates
carbohydrates are also known as ____
sugars
simplest form of carbohydrate
monosaccharide
monosaccharides
- glucose
- fructose
- galactose
- ribose
two chemically bounded monosaccharides
disaccharides
disaccharides:
- sucrose
- lactose
- maltose
glucose + fructose =
sucrose
glucose + galactose =
lactose
two or more monosaccharides
polysaccharides
polysaccharides:
- starch
- glycogen
- cellulose
most abundant organic chemical in the world
cellulose
2 simplest carbohydrates:
- glyceraldehyde
- dihydroxyacetone
sweet colorless crystalline solid that is an intermediate compound in carbohydrate metabolism
glyceraldehyde
primarily used as an ingredient in sunless tanning products
dihydroxyacetane
4 major types of carbohydrates
- monosaccharides
- disaccharides
- oligosaccharides
- polysaccharides
glucose is known by either:
- dextrose
- grape sugar
- blood sugar
also known as levulose, sweetest common sugar
fructose
covalent bond which links a carbohydrate molecule to another group
glycosidic bond
glucose + glucose =
maltose
carbohydrate with at least two but not more than six monosaccharide units linked together
oligosaccharides
large molecule consisting of unbranched chains
amylose
large molecule with branched chains
amylopectin
even more complex polysaccharides and act as labels to help the immune system differentiate an animals own cells from invading bacteria
antigens
part of connective tissue found in joints
glycosaminoglycans
fatty acids or their derivatives and are insoluble in water but soluble in organic solvents
lipids
also known as fat tissues or fatty tissues
adipose tissue
energy storing cells that contain large globules of fat
adipocytes
simple lipid
triglyceride
compound lipid
phospholipid
steroid
cholesterol
miscellaneous lipid
lipoprotein
simple lipids include ____, ____, and ____
- fats
- oils
- waxes
triesther derivatives of glycerol and three fatty acid molecules
fats and oils
from animals except fish oil; saturated
fats
from plants; unsaturated
oils
why do lipids aggregate in aqueous solutions?
to minimize their contact with water
uncontrolled lipid aggregation can lead to
atherosclerosis
metabolic disease in which there is a buildup of cholesterol-filled deposits called plaque on the inner walls of arteries
atherosclerosis
unsaturated fatty acid of a type as a result of the hydrogenation process
trans fat
reaction that turns oil into soap
saponification
four bases found in DNA
- adenine
- cytosine
- guanine
- thymine
2 nucleic acids
- deoxyribonucleic acid (DNA)
- ribonucleic acid (RNA)
derivatives of nucleosides that contain one or more phosphate groups
nucleotides
relative location of genes and DNA in a cell
cell - nucleus - chromosomes - DNA - genes
“cell - nucleus - chromosomes - DNA - genes” meaning
genes are found in the DNA, which in turn is found in the chromosomes, and chromosomes are found in the nucleus of a cell
formation of two daughter cells when a parent cell undergoes cell division
mitosis
splitting of a cell soo tat the number of chromosomes is reduced to half of the original amount;
prepares the way for sexual reproduction
meiosis
example of a cancer drug that causes an abortive DNA replication
gemcitabine
drug that has a flat structure which allows it to slip between DNA bases and disrupt replication
cisplatin
consist of a single polymeric strand of nucleotides instead of a double helix
RNA
RNA contains the pyrimidine base _____ instead of thymine
uracil
any gene that causes cancer
oncogene
programmed cell death
apoptosis
caused by genetic or chromosomal changes
mutations
agent that causes the mutation
mutagen