last one Flashcards

1
Q

What is a spongiform enecpthlopthy of huamns

A

Jakob syndrom

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2
Q

Budding or exocytosis of viruses from host cell can result in

A

Eneveloped animal viruses

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3
Q

What would exit a host cell by lysis

A

Non enveloped viruses

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4
Q

Sheep and goats are affected by which prion diseas

A

Scrapies

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5
Q

Which structure of viruses contribute most to viral adsportion into host cells

A

All of the above ( Enevelope, capsid, matriz protiens, shealth)

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6
Q

What is a term that describes the sepcturm of speficic cells a virus can infect

A

host range

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7
Q

Viral spikes are important for which step of viral replication

A

Adsorption

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8
Q

RNA viruses wit __ genome and ___ rna contain nuclear acids that must be converted before translation

A

single and negative

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9
Q

In geneeral most __ virsues muplty in te host cells while most ___ multiply in the host cell cytoplams

A

DNA. RNA

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10
Q

Which of the following are larger than viruses

A

All of the above

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11
Q

The nucleocapid is made up of __ and ___

A

NA and capsid protiens

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12
Q

Whata re functions of the capsid and envelop

A
  • prottection from external elemnts and chemicals
  • Viral adsportion into host celll
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13
Q

Characteritics of a virus define its host range

A

Virus only bind to specific protien/receptors in digle tossue type

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14
Q

All of the following are prion disease except

A

Hemorrhadic fever

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15
Q

RNA viruss with ___ genome and ___ RNA can immediatly translate thier genome to protiens

A

Single, postivite

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16
Q

Pseudomonas aeruginosa typically is associated with infection in patients with

A

Burns, wounds and Cystic fi

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17
Q

__ acted as accidental host in the pathogensis of the plague ( Yersina pestis)

A

Humans

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18
Q

transmission of bacteria by fecal oral route can be prevented by the floow method EXCEPT

A

Distribution of antifungals

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19
Q

Which of the following are true of shigella

A

They produce shiga toxins

20
Q

What is generally true of all gram NEG bacilli

A

All have outer membrane lipo.

21
Q

__ can be aquired from contaminated fountains or water soruces

A

legionella pneumophila

22
Q

Enterohemorrhaig E.COIL causes

A

Hemolytic urimc syndrome

23
Q

Stenotrophmonas Maltophila

A

Can grow on antimicrobial soap

24
Q

Toxin produced by ___ aralyzes the cillia preveting the movement of muscus in the resp. tract

A

Bordell pertussis

25
Q

Which strain of E. coli causes hemolytic uremic syndrome

A

Enterohemorrhagic

26
Q

__ is a common cause of nosocomial infections in host with cystic fibrosis

A

P. Aeruginosa

27
Q

Y. Pestis makes the coagulase enzyme. How does this virualnce factor INCREASE the spead of this bcaterial infection

A

Coagulase clost blood preventing the flea from acquring nutrients

28
Q

All are ture or legionella pnempliha except

A

Is communicable

29
Q

What is generally true of all gram neg bacilli

A

All ahev a outer membrane lipo.

30
Q

Which of the follwoing events will likley lead to antibiotic resistance

A

All of the above ( Conjunction, transfrmation, over exposure, random mutation in genes)

31
Q

Which would be a poor target for selective toxic drug

A

Ribosomes

32
Q

All are true about interderons expect

A

They are procded by b cells

33
Q

__ inhibit protien synthess by targeting tRNA

A

Teracyclines

34
Q

__ are newly devloped class of antibitoics used to treat muli drug reistant bacterialincetion like VRE and MRSA

A

Oxazolidinones

35
Q

Quinolones inhibit nucleic acid synthesis by

A

Inhibiting DNA helicases

36
Q

Which statment describes third gen

A

Borad specturm

37
Q

Sulfonamides blocking folic acd syntheis preventing binding of PABA to active site to enzyme required for it cinversion to folic acid an exmaple of

A

Competitive inhibition

38
Q

Azidothymidine is used to treat

A

HIV and AIDS

39
Q

Which of the following drugs targets mRNA and inhibting protien synthesis

A

Aminoglycosides

40
Q

Tetracyclines are a borad specturm drug that treat STI , rocky omutain spotted fever and lyme diseas. What is the mechanism of action

A

TARGET tRNA to block protien synthesis

41
Q

Newest drug therpy include optimizing existing immune systme to treat cancer gential warts and other disease which of the follwoing is a current therpy clinic

A

Interferons

42
Q

Which of teh follwoing is not true of cephalosporins

A

they inhibit nuclic acid synthesis

43
Q

which of the follwoing event will likely lead to antiboitic resiatnse

A

ALl of the above ( Over exposure, conjunation/trans, random muations)

44
Q

__ is a term that desribe show a drug should kill or inhibit cells withut simultaneoulu damaging host tissue

A

Slectivtly toxcity

45
Q

What molecue does penecillin target

A

Penicellin binding protien