Last Day Notes Flashcards

1
Q

What forms the resting potential in muscles and nerves?

A

Sodium potassium exchanged

Na - K pump

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2
Q

Which Na or k out?

A

3 Na out

2 K in!

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3
Q

Why resting potential is mainly formed by K?

A

It has open K channels that are permeable while NA channels can’t leave the cell!

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4
Q

What counter the K concentration?

A

Negatively protein anions

- chloride anions

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5
Q

Why does Na plays a minor role in resting potential ?

A

Very little in the cell (0.9)

No Na permeability through membrane

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6
Q

To measure resting potential of an ion you need

A

Nernest equation in which it needs
Ideal gas constant
Faraday’s constant
Temperature in kelvin!

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7
Q

Properties of action potentials?

A

Uniform shapes
Made my short ion movements across membranes
Translate information by frequency modulation

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8
Q

Hyper polarization = refractory period is when?

A

Slow activation of the gate when +35 to -90 Mv

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9
Q

Conductance of Na is much more higher than

A

K!

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10
Q

Steps in excitation-coupling mechanism?

A

Ap spread through sarcoplasmic reteculim and T rubles causing Ca release by DHPRs = voltage gated channels in sarcolemma that opens Ca release channels called ryanodine receptors!

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11
Q

A voltage sensor of Ca in T tubles is

A

DHPRs ! Which is an L type

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12
Q

A motor unit is

A

A group of fibers innervated by a single lower motor neuron

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13
Q

Type 1 muscles are used in

A

Greater force shorter period activity like jumping, running

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14
Q

Characteristic of fast fibers?

A
Glycolytic enzyme 
Few mitochondria
Less blood supply
Great in strength
Extensive sarcoplasmic reticulum
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15
Q

Function of titin

A

Connects actin and myofibrils together

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16
Q

A band is where

A

Actin and myosin overlap

17
Q

I band is

A

Only actin!

18
Q

H zone ?

A

Only myosin!

19
Q

Z line is in the center of

A

I bands and it’s the start of a sarcomere

20
Q

What’s constant and what shortens in a muscle contraction?

A

A band constant

I , H bands and sarcomeres shorten!

21
Q

Load relation with velocity?

A

No load = rapid muscle contraction!

Heavier load= slower contraction

22
Q

Clinical application of ncv

A

Detect neuropathy (demyelination )
Progression of injure have low ncv
Determine whether weaknes is due to muscle or nerve!

23
Q

Joint pain must be distinguished from?

A

Other soft tissue or articulating bone pathologies

24
Q

The joint pain is unlikely due to arthritis if?

A

The range of motion is preserved but their is tenderness on paplation!