Biochemistry

Question 1

What is the ups and downs of FA oxidation ?

Answer 1

Efficient but requires mobilization and time

Question 2

At the beginning of exercise energy is coming from?

Answer 2

Creatine phosphate

Question 3

What activates glycolysis in contracting muscle??

Answer 3

Ca !

Question 4

Ca would activate?

Answer 4

PDH phosphatase!

Question 5

Biochemical features collagen

Answer 5

Low solubility high molecular weight
Unusual amino acid sequence
Many different isoforms

Question 6

Why collagen forms fibrous structure

Answer 6

Because of low solubility and mechanical strength

Question 7

When three collagen polypeptide assemble they form?

Answer 7

A triple helix and not a alpha helix!

Question 8

Importance of proline?

Answer 8

Prevents excessive flexibility and form extended structures

Question 9

Modifications on collagen?

Answer 9

Hydroxylation of proline and lysine And glycosalation

Question 10

Importance of lysine oxidase ?

Answer 10

Assembly of tropocollagen into fibrils and fibers by covalent cross linking

Question 11

What forms a tendon

Answer 11

Collagen type 1 embedded in proteoglycans

Question 12

Importance of purines

Answer 12

Part of coenzyme structure
Signaling molecule
Essential for nucleic acid
Carriers of activated intermediates

Question 13

Dietary purines and nucleic acid

Answer 13

No they don’t participate in nucleic acid they are excreted as Uric acid

Question 14

For DNA production an enxzyme is required that requires ?

Answer 14

Ribonucleotide reductase that uses ATP TO GET ACTIVATED While datp deactivated

Question 15

Characteristic of mitochondrial Dina

Answer 15

Has 2 origin of replication
2-10 copies
Encodes for 37 gene
No introns no histones
Much smaller and cyclic