Laminitis Flashcards
what is another word for laminitis?
founder
does a horse stand on the ground?
no it is suspended by laminae inside a hoof capsule attached to P3
what happens with laminae is weakened by injury?
normal forces acting on digit cause shearing/tearing of laminae
how does the digit slip inside the hoof capsule downwards during laminitis?
weight of horse and rotation from pull of deep digital flexor
what are clinical signs of laminitis?
what is wrong?
widened white line - stretched laminae
Describe laminitis grade 1-4
what are the causes of laminitis?
endolrcrinopathic laminitis
enzymatic associated laminitis
support limb overload laminitis
black walnut toxicity
steroid induced laminitis
heat induced laminitis
what are the two examples of endocrinopathic laminitis?
equine metabolic syndrom/insulin dysfunction
pituitary pars intermedia dysfunction
what model is use to study endocrinopathic laminitis?
hyperinsulinemic model
what model is use to study enzymatic associated laminitis?
SIRS/endotoxemia
What is the pathophysiology of enzymatic model of laminitis?
-accumulates leukocytes in lamellar tissue
-metric metalloproteinases up regulated and cause basement membrane damage
what is the pathophysiology of endocrinopathic laminitis?
lamellar epithelial cell stretching
not induced by inflammation
what is the pathophysiology of support limb laminitis?
loading cycle (offloading and loading the feet) through walking, or shifting weight when standing still, helps to maintain BF to lamellar tissue
stop moving so BF reduced
what does the clinical damage in laminitis?
forces acting on digit (weight of horse)
How is laminitis diagnosed?
radiographs - stand horse evenly on blocks and take both later and dorsal palmar (DP) views
what are the abnormal signs seen in an acute laminitis radiograph?
jet line - edema of laminae
possibly no overt changes
what are the abnormal signs seen in an chronic laminitis radiograph?
ski tipping of P3
loss of parallel between dorsal hoof wall and dorsal P3
medial to lateral asymmetry
sinking