Approach to Medical Diseases of Equine Small Intestine Flashcards

1
Q

what is anteritor enteritis?

A

inflammatory/infectious disease of duodenum and proximal jejunum

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2
Q

what is another name for anterior enteritis?

A

duodenitis-proximal jejunitis/DPJ

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3
Q

what is DPJ characterized by?

A

voluminous SI secretion
functional ileus
copious gastric reflux

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4
Q

what is the pathophysiology of anterior enteritis?

A

Clostridium difficile spores ingested and enter the stomach > spores then pass through pylorus to reach the duodenum > proximal SI rich in bile acids secreted via major duodenal papilla > spores interact with bile and germinate into vegetative cells > cells multiply, colonize, and produce toxins > epithelial damage and inflammation > ileus and colic signs

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5
Q

what is the heart rate and gastric reflux of a colic horse?

A

HR - greater than 60
Gastric Reflux - greater than 8L

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6
Q

what is the primary differential diagnosis for anterior enteritis?

A

strangulating SI lesion

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7
Q

what are the therapeutic goals for AE?

A
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8
Q

what causes equine proliferative enteropathy?

A

Lawsonia intracellularis

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9
Q

what type of horse is primarily affected by equine proliferative enteropathy?

A

weanlings

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10
Q

how do you treat equine proliferative enteropathy?

A

long term antibiotics

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11
Q

what are the clinical signs of equine proliferative enteropathy?

A

weight loss, unthriftiness, edema, depression, fever, hypoproteinemia

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12
Q

what are the therapeutic goals for equine proliferative enteropathy?

A
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13
Q

what are the types of IBD reported in horses?

A

eosinophilic enterocolitis
Idiopathic focal eosinophilic enteritis
Multi-systemic eosinophilic epitheliotropic disease (MEED)
Grandulomatous enteritis
Lymphocytic-plasmacytic enterocolitis

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14
Q

what is the presentation of IBD?

A

weight loss, +/- colic, +/- diarrhea

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15
Q

what do you do when you get to a colic call and the HR is above 60?

A

pass a nasogastric tube

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16
Q

how do you treat IBD?

A

corticosteroids, surgical excision, parasite control, diet

17
Q

what would you expect to feel on a rectal for anterior enteritis/DJP?

A

loops of distended, fluid-filled SI

18
Q

Do anterior enteritis patients typically have a fever?

A

yes

19
Q

Before transferring a DJP horse for referral what do you do?

A

give flunixin meglumine
leave in nasogastric tube

20
Q

what can high fibrinogen indicated on a CBC in a colic horse?

A

signs of system inflammation

21
Q

what can a high total protein indicate on BW in a colic horse?

A

dehydration, hemoconcentration

22
Q

what does low electrolytes indicate on BW in a colic horse?

A

loosing fluid into GI tract

23
Q

what does high creatine indicate on BW in a colic horse?

A

dehydration, hemoconcentration

24
Q

what does high bilirubin indicate on BW in a colic horse?

A

anorexic horse
bilirubin rises
secondary problem

25
Q

what does high GGT indicate on BW in a colic horse?

A

inflammation in biliary tracts
secondary problem

26
Q

what does a high lactate value on BW indicate for a colic horse?

A

hypovolemic, not perfusing properly

27
Q

what does a high protein on abdominocentesis indicate for a colic horse?

A

inflammation so losing protein into abdomen

28
Q

what are some indicators of anterior enteritis?

A

HR dec after reflux removed
fever present
pain controlled early on with low dosing of analgesics

29
Q

What value should potassium NOT exceed when added to fluids?

A

0.5 mEq/kg/hr

30
Q

what is the maintenance IV fluid rate for an adult horse?

A

maintenance = 2-3 mL/kg/hr

31
Q

Calculate the IV fluid rate for a horse weighing 450kg

A

3mL x 450kg = 1.3L/hr

32
Q

how is anterior enteritis treated?

A

antibiotics, prokinetics, anti-inflammatories, laminitis prevention, parenteral nutrition, fluids (with electrolytes), colloids

33
Q

what are your differentials?

A

parasitism
Equine proliferative enteropathy
IBD - granulomatous enteritis

34
Q

Given these results what do you think the foal with colic has?

A

Equine proliferative enteropathy

35
Q
A
36
Q
A