Lactate Transport Flashcards

1
Q

What is said to be true about the highest Lactate Threshold pressure when given on a figure as an example?

A

Highest Lactate pressure = Longer a person can exercise

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2
Q

How many Carbons does Lactate have?

A

It’s a 3 Carbon Glucose Molecule

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3
Q

What is Lactate’s role during transport?

A

To help buffer & help transfer/push H+ out of the cell

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4
Q

At physiological pH, is there “Lactic Acid”?

A

No, just lactate and protons (H+)

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5
Q

What percent of all Lactate is oxidized during exercise?

A

80%

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6
Q

True or False: Lactate is a 3C fragment of Glucose.

A

True

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7
Q

What facilitates the transport of pyruvate across the inner mitochondrial membrane?

A

By MCT1

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8
Q

What ‘COX’ stand for?

A

Cytochrome Oxidase

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9
Q

Where is O2 utilized in cells during Lactate Oxidation?

A

In the Mitochondrial COX.

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10
Q

How does Lactate become oxidized?

A

Lactate Transporter gets Lactate oxidized to pyruvate via Mitochondrial LDH.

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11
Q

Lactate Threshold is the best measure of what?

A

Performance

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12
Q

Which system of energy uses Oxygen?

A

System 3 (Aerobic/Mitochondria Metabolism)

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13
Q

What is the point at which blood lactate accumulates substantially above resting concentrations during exercise of increasing intensity?

A

Lactate Threshold

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14
Q

What are the differences in Lactate Threshold max between untrained and trained people?

A

Untrained: 50-65%
Trained: 65-80%

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15
Q

True or False: LT is usually expressed as an average of maximal oxygen uptake.

A

False, it’s expressed as a percentage of maximal oxygen uptake.

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16
Q

True of False: LT is related to exercise intensity & demand for ATP, and isn’t anaerobic.

A

True.

17
Q

True of False: A low LT can indicate potential for better endurance performance.

A

False, the higher the LT, the better potential for increased endurance performance.

18
Q

Lactate Threshold is the rate at which Lactate ___________ (Ra) __________ Lactate Clearance (Rd).

A

Production; exceeds

19
Q

At rest, Lactate appearance is about _____ of Glucose appearance and disappearance.

A

Half

20
Q

Ra (rate of ____________) is matched by Rd (rate of ______________) and is (below/above) LT

A

Appearance; Disappearance; Below

21
Q

As exercise intensity increases, what happened with respect to ATP production, Ra of Lactate in venous blood, and the rate of Lactate removal from the blood (Rd)?

A

ATP Production: Greater demand for rapid ATP production
Ra of Lactate in blood: Increases
Rd of Lactate in blood: Exceeded

22
Q

What organs removes Lactate, how, and what happens to the total concentration of Lactate?

A

Heart, Liver, Kidney, & resting Muscles; Total Lactate concentration increases.

23
Q

Does increased LT allow for exercise at a higher/lower % VO2 max?

A

Higher

24
Q

Does increased LT increase/decrease exercise pace?

A

Increase

25
Q

How could you improve training techniques?

A

Putting a HR monitor on a person and measuring their LT.

26
Q

What improves the ability to remove Lactate during exercise?

A

Training

27
Q
What happens to the following when you increase the ability to remove Lactate during exercise:
A) Rd
B) Ra
C) Mitochondrial size/mass
D) Muscle buffering capacity
A

A) Rd = Increases

B) Ra = Decreases

C) Mitochondrial size/mass = Increases

D) Muscle buffering capacity = Increases

28
Q

Which of the following increases to a greater degree with improved training, Lactate or VO2 max?

A

Lactate

29
Q

What is Rd (Lactate removal after exercise dependent upon?

A

Exercise intensity and duration

Cool-down/Active recovery