Lactate Transport Flashcards
What is said to be true about the highest Lactate Threshold pressure when given on a figure as an example?
Highest Lactate pressure = Longer a person can exercise
How many Carbons does Lactate have?
It’s a 3 Carbon Glucose Molecule
What is Lactate’s role during transport?
To help buffer & help transfer/push H+ out of the cell
At physiological pH, is there “Lactic Acid”?
No, just lactate and protons (H+)
What percent of all Lactate is oxidized during exercise?
80%
True or False: Lactate is a 3C fragment of Glucose.
True
What facilitates the transport of pyruvate across the inner mitochondrial membrane?
By MCT1
What ‘COX’ stand for?
Cytochrome Oxidase
Where is O2 utilized in cells during Lactate Oxidation?
In the Mitochondrial COX.
How does Lactate become oxidized?
Lactate Transporter gets Lactate oxidized to pyruvate via Mitochondrial LDH.
Lactate Threshold is the best measure of what?
Performance
Which system of energy uses Oxygen?
System 3 (Aerobic/Mitochondria Metabolism)
What is the point at which blood lactate accumulates substantially above resting concentrations during exercise of increasing intensity?
Lactate Threshold
What are the differences in Lactate Threshold max between untrained and trained people?
Untrained: 50-65%
Trained: 65-80%
True or False: LT is usually expressed as an average of maximal oxygen uptake.
False, it’s expressed as a percentage of maximal oxygen uptake.
True of False: LT is related to exercise intensity & demand for ATP, and isn’t anaerobic.
True.
True of False: A low LT can indicate potential for better endurance performance.
False, the higher the LT, the better potential for increased endurance performance.
Lactate Threshold is the rate at which Lactate ___________ (Ra) __________ Lactate Clearance (Rd).
Production; exceeds
At rest, Lactate appearance is about _____ of Glucose appearance and disappearance.
Half
Ra (rate of ____________) is matched by Rd (rate of ______________) and is (below/above) LT
Appearance; Disappearance; Below
As exercise intensity increases, what happened with respect to ATP production, Ra of Lactate in venous blood, and the rate of Lactate removal from the blood (Rd)?
ATP Production: Greater demand for rapid ATP production
Ra of Lactate in blood: Increases
Rd of Lactate in blood: Exceeded
What organs removes Lactate, how, and what happens to the total concentration of Lactate?
Heart, Liver, Kidney, & resting Muscles; Total Lactate concentration increases.
Does increased LT allow for exercise at a higher/lower % VO2 max?
Higher
Does increased LT increase/decrease exercise pace?
Increase
How could you improve training techniques?
Putting a HR monitor on a person and measuring their LT.
What improves the ability to remove Lactate during exercise?
Training
What happens to the following when you increase the ability to remove Lactate during exercise: A) Rd B) Ra C) Mitochondrial size/mass D) Muscle buffering capacity
A) Rd = Increases
B) Ra = Decreases
C) Mitochondrial size/mass = Increases
D) Muscle buffering capacity = Increases
Which of the following increases to a greater degree with improved training, Lactate or VO2 max?
Lactate
What is Rd (Lactate removal after exercise dependent upon?
Exercise intensity and duration
Cool-down/Active recovery