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MLSP > LABORATORY BIOSAFETY AND BIOSECURITY > Flashcards

LABORATORY BIOSAFETY AND BIOSECURITY Flashcards

1
Q

origins of biosafety is rooted in the US biological weapons program in year _________

A

1943

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2
Q

first scientific director of Camp Detrick. He was tasked with establishing the biological weapons programs for defensive purposes

A

Ira L. Baldwin

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3
Q

US president Richard Nixon terminated such program

A

1969

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4
Q

he designed modifications for biosafety at Camp Detrick

A

Newell A. Johnson

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5
Q

He developed Class III safety cabinets and laminar flow hoods to address specific risks.

A

Newell A. Johnson

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6
Q

formation of American Biological Safety Association (ABSA)

A

1984

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7
Q

he described the use of mechanical pipettors to prevent laboratory-acquired infections

A

Arnold Wedum (1907-1908)

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8
Q

year when pharmaceutical company in Pennsylvania developed a ventilated cabinet to prevent infection from Mycobacterium tuberculosis

A

1909

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9
Q

year when WHO pursued the eradication of the Small pox virus. Serious concerns about biosafety practices worldwide were raised.

A

1967

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10
Q

year when CDC published the Classification of Etiologic Agent on The Basis of Hazard

A

1974

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11
Q

CDC published the Classification of Etiologic Agent on The ____________________

A

Basis of Hazard

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12
Q

year when NIH published the Guidelines for Research Involving Recombinant DNA Molecules. It explained in detail the microbiological practices, equipment and facility necessarily corresponding the four ascending levels of physical containment.

A

1976

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13
Q

year when published first edition of the biosafety in microbiological and biomedical laboratories. These documents established the model of biosafety containment levels with certain agents.

A

1984

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14
Q

it is the technical means of mitigating the risk of accidental infection from or release of agents in the laboratory setting as well as in the community and environment it is situated in.

A

Biosafety levels

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15
Q

they ensure that the proper equipment and facility controls are in placed based on the specified biosafety levels of the laboratory

A

Biosafety officers

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16
Q

year when Alfred Wedum and Morton Reitman analyzed multiple epidemiological studies of laboratory-based outbreaks.

A

1966

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17
Q

________ and ________ analyzed multiple epidemiological studies of laboratorybased outbreaks.

A

Alfred Wedum and Morton Reitman

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18
Q

year when US government enacted the Select Agent Regulations to monitor the transfer of select list of biological agents

A

1906

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19
Q

year when of Select Agent Regulations was revised

A

2012

20
Q

law that established four schedules of select agents that are subject to different reporting and handling requirements

A

Infectious Disease Control Law

21
Q

Other countries biosecurity regulations for bioscience facilities:

A
  1. Biological Agents and Toxins Act
  2. Act on Prevention of Infectious Diseases (2005)
  3. Infectious Disease Control Law
22
Q

this act/law require institutions that work with listed “highly dangerous pathogens” to implement laboratory biosafety and biosecurity requirements.

A

Act on Prevention of Infectious Diseases (2005)

23
Q

published the CEN workshop agreement 15793.

A

Comité Européen de Normalisation

24
Q

This agreement intended to maintain a biorisk management system among diverse organizations and set out performance-based requirements for implementing a national biosafety system

A

Comité Européen de Normalisation

25
Q

INTERNATIONAL GUIDELINES LABORATORY that includes information on the different levels of containment laboratories (biosafety levels 1-4), different types of biological safety cabinets, good microbiological techniques and how to disinfect and sterilize equipment.

A

Laboratory Biosafety Manual

26
Q

provides an international regulatory framework to ensure “an adequate level of protection in the field of safe transfer, handling and the use of living modified organism resulting from modern biotechnology”

A

Cartagena Protocol on Biosafety

27
Q

Procedures:
Evaluation of proposal for biosafety concerns
Procedures and guidelines on the introduction, movement and field release of regulated materials
Physicochemical and biological containment

A

National Committee On Biosafety Of The Philippines (NCBP)

28
Q

it promotes biosafety as a scientific discipline and provides guidance to its members on the regulatory regime present in North America

A

American Biological Safety Association

29
Q

acts as a professional society for biosafety professionals in Asia - pacific region. Active members of the international biosafety working group are required to directly contribute to the development of the best biosafety practices.

A

Asia Pacific Biosafety Association

30
Q

focuses on encouraging and communicating among its members information and issues on biosafety and biosecurity as well as emerging legislation and standards

A

European Biological Safety Association (EBSA)

31
Q

assist DA and DOH in their efforts to create a national policy and implement plan for laboratory biosafety and biosecurity

A

Philippine Biosafety And Biosecurity Association (PhBBA)

32
Q

a non government and non profit association that works to serve the emergent concerns of biological risk management in various professional fields such as in health, agriculture and technology sectors throughout the country.

A

Biological Risk Association Philippines (BRAP) -

33
Q

Containment principles, technologies and practices that are implemented to prevent unintentional exposure to pathogens and toxins, or their accidental release.

A

Biosafety

34
Q

refers to the protection, control and accountability for valuable biological materials within laboratories, in order to prevent their unauthorized access, loss, theft, misuse, diversion or intentional release

A

Biosecurity

35
Q

he created the biohazard symbol used in labeling biological materials carrying significant health risks

A

Charles Baldwin

36
Q

focuses on the laboratory procedures and practices necessary to prevent exposure to and acquisition of infections

A

Biosafety

37
Q

focuses on the maintenance of secure procedures and practices in handling biological materials and sensitive information

A

Biosecurity

38
Q

Risk group classification for humans and animals is based on agent’s:

A 
Pathogenicity
Mode of transmission
Host range
Availability of preventive measure
Effective treatment
39
Q

includes microorganisms that are unlikely to cause human or animal disease.

A

Risk group 1

40
Q

includes microorganisms that are unlikely to be a significant risk to laboratory workers and community, livestock or environment. Laboratory exposure may cause infection, however, effective treatment and preventive measures are available while the risk of spread is limited.

A

Risk group 2

41
Q

include microorganisms that are known to cause serious diseases to humans or animals and may present a significant risk to

A

Risk group 3

42
Q

includes microorganisms that are known to produce life threatening diseases to humans or animals. It represents a significant risk to laboratory workers . They bring about high individual and community risk.

A

Risk group 4

43
Q

is suitable for work involving viable microorganisms that are defined and with well- characterized strains known not to cause disease in humans.

A

Biosafety level 1 (BSL-1)

44
Q

is basically designed for laboratories that deal with indigenous moderate risk agents present in the community. It observes practices equipment, and facility design that are applicable to clinical, diagnostic and teaching laboratories consequently observing good

A

Biosafety level 2 (BSL-2)

45
Q

puts emphasis on primary and secondary barriers in the protection of the personnel, the community, and the environment from infectious aerosol exposure

A

Biosafety level 3 (BSL-3)

46
Q

Is required for work with dangerous and exotic agents that pose high individual risks of life-threatening diseases that may be transmitted via the aerosol route, for which there are no available vaccines or treatment.

A

Biosafety level 4 (BSL 4)

MLSP (9 decks)

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