LABORATORY BIOSAFETY AND BIOSECURITY

Question 1

origins of biosafety is rooted in the US biological weapons program in year _________

Answer 1

1943

Question 2

first scientific director of Camp Detrick. He was tasked with establishing the biological weapons programs for defensive purposes

Answer 2

Ira L. Baldwin

Question 3

US president Richard Nixon terminated such program

Answer 3

1969

Question 4

he designed modifications for biosafety at Camp Detrick

Answer 4

Newell A. Johnson

Question 5

He developed Class III safety cabinets and laminar flow hoods to address specific risks.

Answer 5

Newell A. Johnson

Question 6

formation of American Biological Safety Association (ABSA)

Answer 6

1984

Question 7

he described the use of mechanical pipettors to prevent laboratory-acquired infections

Answer 7

Arnold Wedum (1907-1908)

Question 8

year when pharmaceutical company in Pennsylvania developed a ventilated cabinet to prevent infection from Mycobacterium tuberculosis

Answer 8

1909

Question 9

year when WHO pursued the eradication of the Small pox virus. Serious concerns about biosafety practices worldwide were raised.

Answer 9

1967

Question 10

year when CDC published the Classification of Etiologic Agent on The Basis of Hazard

Answer 10

1974

Question 11

CDC published the Classification of Etiologic Agent on The ____________________

Answer 11

Basis of Hazard

Question 12

year when NIH published the Guidelines for Research Involving Recombinant DNA Molecules. It explained in detail the microbiological practices, equipment and facility necessarily corresponding the four ascending levels of physical containment.

Answer 12

1976

Question 13

year when published first edition of the biosafety in microbiological and biomedical laboratories. These documents established the model of biosafety containment levels with certain agents.

Answer 13

1984

Question 14

it is the technical means of mitigating the risk of accidental infection from or release of agents in the laboratory setting as well as in the community and environment it is situated in.

Answer 14

Biosafety levels

Question 15

they ensure that the proper equipment and facility controls are in placed based on the specified biosafety levels of the laboratory

Answer 15

Biosafety officers

Question 16

year when Alfred Wedum and Morton Reitman analyzed multiple epidemiological studies of laboratory-based outbreaks.

Answer 16

1966

Question 17

________ and ________ analyzed multiple epidemiological studies of laboratorybased outbreaks.

Answer 17

Alfred Wedum and Morton Reitman

Question 18

year when US government enacted the Select Agent Regulations to monitor the transfer of select list of biological agents

Answer 18

1906

Question 19

year when of Select Agent Regulations was revised

Answer 19

2012

Question 20

law that established four schedules of select agents that are subject to different reporting and handling requirements

Answer 20

Infectious Disease Control Law

Question 21

Other countries biosecurity regulations for bioscience facilities:

Answer 21

1. Biological Agents and Toxins Act
2. Act on Prevention of Infectious Diseases (2005)
3. Infectious Disease Control Law

Question 22

this act/law require institutions that work with listed “highly dangerous pathogens” to implement laboratory biosafety and biosecurity requirements.

Answer 22

Act on Prevention of Infectious Diseases (2005)

Question 23

published the CEN workshop agreement 15793.

Answer 23

Comité Européen de Normalisation

Question 24

This agreement intended to maintain a biorisk management system among diverse organizations and set out performance-based requirements for implementing a national biosafety system

Answer 24

Comité Européen de Normalisation

Question 25

INTERNATIONAL GUIDELINES LABORATORY that includes information on the different levels of containment laboratories (biosafety levels 1-4), different types of biological safety cabinets, good microbiological techniques and how to disinfect and sterilize equipment.

Answer 25

Laboratory Biosafety Manual

Question 26

provides an international regulatory framework to ensure “an adequate level of protection in the field of safe transfer, handling and the use of living modified organism resulting from modern biotechnology”

Answer 26

Cartagena Protocol on Biosafety

Question 27

Procedures: Evaluation of proposal for biosafety concerns Procedures and guidelines on the introduction, movement and field release of regulated materials Physicochemical and biological containment

Answer 27

National Committee On Biosafety Of The Philippines (NCBP)

Question 28

it promotes biosafety as a scientific discipline and provides guidance to its members on the regulatory regime present in North America

Answer 28

American Biological Safety Association

Question 29

acts as a professional society for biosafety professionals in Asia - pacific region. Active members of the international biosafety working group are required to directly contribute to the development of the best biosafety practices.

Answer 29

Asia Pacific Biosafety Association

Question 30

focuses on encouraging and communicating among its members information and issues on biosafety and biosecurity as well as emerging legislation and standards

Answer 30

European Biological Safety Association (EBSA)

Question 31

assist DA and DOH in their efforts to create a national policy and implement plan for laboratory biosafety and biosecurity

Answer 31

Philippine Biosafety And Biosecurity Association (PhBBA)

Question 32

a non government and non profit association that works to serve the emergent concerns of biological risk management in various professional fields such as in health, agriculture and technology sectors throughout the country.

Answer 32

Biological Risk Association Philippines (BRAP) -

Question 33

Containment principles, technologies and practices that are implemented to prevent unintentional exposure to pathogens and toxins, or their accidental release.

Answer 33

Biosafety

Question 34

refers to the protection, control and accountability for valuable biological materials within laboratories, in order to prevent their unauthorized access, loss, theft, misuse, diversion or intentional release

Answer 34

Biosecurity

Question 35

he created the biohazard symbol used in labeling biological materials carrying significant health risks

Answer 35

Charles Baldwin

Question 36

focuses on the laboratory procedures and practices necessary to prevent exposure to and acquisition of infections

Answer 36

Biosafety

Question 37

focuses on the maintenance of secure procedures and practices in handling biological materials and sensitive information

Answer 37

Biosecurity

Question 38

Risk group classification for humans and animals is based on agent’s:

Answer 38

``` Pathogenicity Mode of transmission Host range Availability of preventive measure Effective treatment ```

Question 39

includes microorganisms that are unlikely to cause human or animal disease.

Answer 39

Risk group 1

Question 40

includes microorganisms that are unlikely to be a significant risk to laboratory workers and community, livestock or environment. Laboratory exposure may cause infection, however, effective treatment and preventive measures are available while the risk of spread is limited.

Answer 40

Risk group 2

Question 41

include microorganisms that are known to cause serious diseases to humans or animals and may present a significant risk to

Answer 41

Risk group 3

Question 42

includes microorganisms that are known to produce life threatening diseases to humans or animals. It represents a significant risk to laboratory workers . They bring about high individual and community risk.

Answer 42

Risk group 4

Question 43

is suitable for work involving viable microorganisms that are defined and with well- characterized strains known not to cause disease in humans.

Answer 43

Biosafety level 1 (BSL-1)

Question 44

is basically designed for laboratories that deal with indigenous moderate risk agents present in the community. It observes practices equipment, and facility design that are applicable to clinical, diagnostic and teaching laboratories consequently observing good

Answer 44

Biosafety level 2 (BSL-2)

Question 45

puts emphasis on primary and secondary barriers in the protection of the personnel, the community, and the environment from infectious aerosol exposure

Answer 45

Biosafety level 3 (BSL-3)

Question 46

Is required for work with dangerous and exotic agents that pose high individual risks of life-threatening diseases that may be transmitted via the aerosol route, for which there are no available vaccines or treatment.

Answer 46

Biosafety level 4 (BSL 4)