BIORISK MANAGEMENT Flashcards
The risk associated to biological toxins or infectious agents.
biorisk
The source of risk may be unintentional exposure to unauthorized access, accidental release or loss, theft, misuse, diversion, or intentional unauthorized release of biohazards.
biorisk
The integration of biosafety and biosecurity to manage risks when
working with biological toxins and infectious agents
biorisk management
“ a system or process to control safety and security risks
associated with the handling or storage and disposal of biological
agents and toxins in the laboratories and facilities.”
biorisk management
BIORISK MANAGEMENT DIVIDED INTO THREE PRIMARY COMPONENTS:
- assessment
- mitigation
- performance
it is anything in the environment that has the potential to cause harm
hazard
it is the possibility that something bad or unpleasant (such as injury or loss) will happen).
risk
The likelihood that an adverse event involving a specific hazard or threat will occur followed by the consequences of that occurrence.
risk
a process where the risk assessment team must identify the hazards and risks of the biological agents to be handled.
define the situation
this process must include a review of how individuals inside and outside the laboratory may be exposed to hazards.
define the risk
this process needs to compare the likelihood and the consequences of infection- either quantitatively or qualitatively.
characterize the risks
this process take into account the adequacy of any existing controls and deciding whether or not the biorisk is acceptable.
determine if risk is available or not
identify the four steps of risk assessment
- define the situation
- define the risks
- characterize the risks
- determine if risk is available or not.
these are action and control measures that are put into place to reduce or eliminate the risks associated with biological agents and toxins.
biorisk mitigation
enumerate the mitigation process (in order)
- elimination
- substitution
- engineering controls
- controls that increase awareness`
- administrative controls (including training)
- personal control
it is the most effective mitigation procedure
elimination
it is the least effective mitigation procedure
personal protection
Involves the total decision not to work with a specific biological agent or even not doing the intended work.
elimination
Replacement of the procedures or biological agent with a similar entity in order to reduce the risks.
substitution
Physical changes in work stations, equipment, production facilities, or any other relevant aspect of the work environment that can reduce or prevent exposure to hazards.
engineering controls
Refers to the policies, standards, and guidelines used to control risks.
administrative controls
Practices and procedures of administrative controls comprise minimizing splashes, sprays and aerosols to avoid ______________________
laboratory-acquired infections.
Devices worn by workers to protect them against chemicals, toxins, and pathogenic hazards in the laboratory
personal protective equipment
Involves a systematic process intended to achieve organizational objectives and goals.
performance evaluation
It helps to highlight biorisk strategies that are not working effectively and measures that are ineffective or unnecessary
performance evaluation
biorisk is the risk associated to _________ or ___________
biological toxins or infectious agents.
The source of risk may be unintentional exposure to unauthorized access, ________________, theft, misuse, diversion, or intentional unauthorized release of biohazards.
accidental release or loss
The integration of ___________ and ___________ to manage risks when working with biological toxins and infectious agents
biosafety and biosecurity
“ a system or process to control safety and security risks associated with the _________ or __________ and _________ of biological agents and toxins in the laboratories and facilities.”
handling or storage and disposal
Define the situation - the risk assessment team must identify the __________ and __________ of the biological agents to be handled.
hazards and risks
Define the risks - must include a review of how individuals inside and outside the laboratory may be exposed to ___________
hazards
Characterize the risks - needs to compare the likelihood and the
consequences of infection, either ________ or ___________.
quantitatively or qualitatively
Determine if the risk is available or not - take into account the _____________ of any existing controls and decide whether or not the biorisk is acceptable.
adequacy
BIORISK MITIGATION - are action and control measures that are put into place to _________ or _______________ associated with biological agents and toxins.
reduce or eliminate the risks
are action and control measures that are put into place to reduce or eliminate the risks associated with biological agents and toxins.
BIORISK MITIGATION
FIVE CONTROL AREAS OF MITIGATION [from most effective to least]
elimination substitution engineering controls controls that increase awareness administrative controls personal protection
Involves the total decision not to work with a specific biological agent or even not doing the intended work.
elimination
Replacement of the procedures or biological agent with a similar entity in order to reduce the risks.
subtitution
Physical changes in work stations, equipment, production facilities, or any other relevant aspect of the work environment that can reduce or prevent exposure to hazards.
engineering controls
Refers to the policies, standards, and guidelines used to control risks.
administrative controls
Practices and procedures of ____________________ comprise minimizing splashes, sprays and aerosols to avoid laboratory-acquired infections.
administrative controls
Devices worn by workers to protect them against chemicals, toxins, and pathogenic hazards in the laboratory
PPE
Involves a systematic process intended to achieve organizational objectives and goals.
Performance Evaluation
It helps to highlight biorisk strategies that are not working effectively and measures that are ineffective or unnecessary
Performance Evaluation
The cycle of performance management
- identify the key issue of concern
- define outcome (indicators and metrics)
- define activities (indicators and metrics)
- collect data and report indicators results
- provide findings from performance indicators
- evaluate and refine performance indicators
