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Pharmacy School Spring P1 > LABA/LAMA/ICS combination products, Mast Cell Stabilizer, Leukotriene Modifiers > Flashcards

LABA/LAMA/ICS combination products, Mast Cell Stabilizer, Leukotriene Modifiers Flashcards

1
Q

Brand: Trelegy Ellipta

A

Generic: Fluticasone/Umeclidinium/Vilanterol

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2
Q

Fluticasone/Umedclidinium/Vilanterol (Brand: Trelegy Ellipta) dosage form

A

Ellipta

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3
Q

Brand: Breztri Aerosphere

A

Generic: Budesonide/Glycopyrrolate/Formoterol Fumarate

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4
Q

Budesonide/Glycopyrrolate/Formoterol Fumarate (Brand: Breztri Aerosphere) dosage form

A

Aerosphere

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5
Q

What are the indications for the LABA/LAMA/ICS combination products?

A

-Fluticasone/Umeclidinium/Vilanterol (Brand: Trelegy Ellipta) is Asthma and COPD (adult dosing for both)
-Budesonide/Glycopyrrolate/Formoterol Fumarate (Brand: Breztri Aerosphere) is COPD only (adult dosing)

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6
Q

What is the Mast cell stabilizer medication?

A

Brand: Intal
Generic: Cromolyn

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7
Q

Cromolyn (Brand: Intal) dosage form and age groups

A

Nebulizer Solution
dosing age: 0-adults

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8
Q

What is the Mast cell stabilizer side effects?

A

-high incidence of unpleasant taste in mouth, rare cardiac arrhythmias, coughing, dyspnea, sore throat, Nausea, Vomiting, Diarrhea if absorbed systemically
-less effective than low-dose ICS
-prevents increase in bronchial hypersensitivity seen in allergy season

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9
Q

Brand: Singulair

A

Generic: Montelukast

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10
Q

Montelukast (Brand: Singulair) classification and dosage form and dosing age

A

Leukotriene modifiers
Tablets (chewable) or Granule Packets
approved for ages 1+

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11
Q

Brand: Accolate

A

Generic: Zafirlukast

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12
Q

Zafirlukast (Brand: Accolate) classification, dosage form and dosing age

A

Leukotriene Modifiers
Tablets
approved for ages 5+

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13
Q

Brand: Zyflo CR

A

Generic: Zileuton

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14
Q

Zileuton (Brand Zyflo CR) classification, dosage form and dosing

A

Leukotriene Modifiers
IR Tablets, ER Tablets
Adult only dosing

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15
Q

Side effects for Leukotriene modifiers

A

neurophysciatric events (agitation, anxiety, abnormal dreams, hallucinations, depression, suicidal thinking), Chrug-Strauss syndrome (rare), increased hepatic transaminases (zafirlukast and zileuton)
-less effect than low dose ICS and ICS/LABA in asthma

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16
Q

What are some counseling tips for Montelukast (Brand: Singulair)?

A

-not for acute relief of symptoms
-Boxed Warning: neuropsychiatric events

17
Q

What are some counseling tips for Zafirlukast (Brand: Accolate)?

A

-Take at least 1 hour before or 2 hours after meals
-can increase INR

18
Q

What are some counseling tips for Zileuton (Brand: Zyflo CR)?

A

-take with food

Pharmacy School Spring P1 (28 decks)

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