Lab studies Flashcards
What is in a Chem 7 panel?
NA+ (Sodium) K+ (Potassium) CL- (chloride) CO2 (Carbon Dioxide) BUN (Blood urea Nitrogen) CR (Creatinine) Glucose
What is the normal range for NA+
135-145
What is the normal range for K+
3.5-5
What is the normal range for CL-
96-106
What is the normal range for CO2
22-26
What is the normal range for BUN
8-23
What is the normal range for Creatinine
0.7-1.4
What is the normal range for Glucose
60-100 or 70-110
What does NA+ do in the body?
Helps nerves and muscles interact
It is the primary extracellular cation
What does hypernatremia cause?
Fluid retention
What does hyponatremia cause?
CHF, renal failure, liver disease and dehydration
If you don’t correct hyponatremia slowly, what can it cause?
Central pontine myelinolysis
What can happen if your sodium drops below 125?
Behavioral problems, twitching and cardiac abnormalities
What electrolyte abnormality is the most dangerous?
Potassium K+
What can hyperkalemia cause?
Tissue breakdown, metabolic acidosis, acute renal failure
What EKG change is indicative of hyperkalemia?
Peaked T waves
P waves will flatten
Bradycardia
What are some symptoms of hyperkalemia?
Abdominal cramping, nausea, hypotension, bradycardia, numbness
What is the treatment for Hyperkalemia?
Goal is to push into cells
Bicarb, insulin, D50 and albuterol
To prevent V-Tach, give calcium gluconate
What medication do you give to excrete
Lasix and Kayexalate
What is the preferred method of administration of K+
Oral
What does hypokalemia cause?
GI/Renal losses, cellular shifts (insulin, hypothermia).
Lasix is a common cause of hypokalemia
What will the EKG show?
Depressed/inverted or flattened T waves
What is the treatment for hypokalemia?
Give 60 mEq of oral K+
If severe you can give 10 mEq IV
What does CL do
Maintains osmotic pressure, helps stomach produce acid and responsible for offsetting NA+ and K+
It is an important role in how kidneys concentrate urine
It tends to shift with NA+
What does CO2 do?
Important for helping maintain acid base balance
What does BUN do
Provides picture of renal clearance and is always paired with CR and increases with age
What does CR do?
Provides picture of renal clearance and produces at a steady rate.
What is total calcium and what does it do? What is the normal range?
It is the most essential electrolyte in the body, mostly in bones
Found in 3 different states: 47% free, dispersed in body fluids, 43% bound to proteins, 10% bound to molecules
8.5-1.2
What can cause hypercalcemia?
Tumor on parathyroid, tuberculosis, thiazide diuretics, kidney transplant
What causes hypocalcemia?
Low level albumin, decreased vitamin D/calcium intake, alcoholism, pancreatitis, renal failure
What are some signs and symptoms of hypocalcemia?
Chvostek’s or Trousseau’s sign
Chvostek sign: cheek muscle spasm when facial nerve tapped in front of ear
Trousseau’s sign: curl up of wrist when BP cuff applied
Treat with calcium gluconate
What is an anion gap?
NA+, CL- and HCO3 factored together to determine anion gap
Considered the poor man ABG
What is a normal Anion Gap?
12 (+/- 4)
(NA) - (CL + HCO3) = Anion gap
In an anion gap acidosis, what level of pH may be treated with Sodium Bicarb
< 7.0
What is in a CBC?
Red blood cells, Hemoglobin, Hematocrit, white blood cells, platelets
What is the normal range for Red blood cells and what do they do?
5 million
Carry O2 to tissue
What is the normal range for hemoglobin and what does it do?
15
Carries O2 from lungs to body
What is the normal range for hematocrit and what does it do?
45%
% of RBC in blood
What is the normal range for white blood cells and what do they do?
4500-11k
Body’s defense, part of immune system
What is the normal range for platelets and what do they do?
150k-400k
Aids in clotting
What is the normal range for total protein and what do they do?
6-8
Helps to fight stuff
What is the normal range for albumin and what does it do?
3.5-5.5
Produced in liver and transports protein
What is the normal range for PT, PTT, and INR?
PT- 10-13 sec
PTT- 25-40 sec
INR- .9-1.3
What is the intrinsic pathway
(Heparin) Triggered by endothelial damage platelets activate initiates clotting Forms clot clot dissolves
What is the extrinsic pathway?
(coumadin) Triggered by damage to tissue Release of tissue thromboplastin highest in brain in placenta platelets activate initiates clot forms clot clot dissolves
What is the treatment for overdose of lovenox or heparin
Pratamine Sulfate
What is the treatment for overdose of coumadin?
Vitamin K
What is measured in a liver function test?
AST, ALT, ALP, Albumin, Billirubin
What is the normal range for ALT and it’s function?What is measured in a liver function test?
7-55
Helps body metabolize protein
What is the normal range for AST and it’s function?
8-48
Helps metabolize alanine (amino acid)
What is the normal range for ALP and it’s function?
45-115
Enzyme in liver, bile ducts and bones. can indicate any blocked bile ducts
What is the normal range for bilirubin and what is it’s function?
0.1-1.2
Produced during normal breakdown of RBC
What is the normal range for lactate and it’s funtion?
0.5-1
Indicates tissue hypo-perfusion or hypoxia
What is the normal range for amylase and what is it’s function?
25-125
Breaks down carbs in food into simple sugars
Testing used to detect pancreatitis
What is the normal range of lipase and it’s funciton?
5-60
Breaks down fats
What is the calculation for urine?
2/1/0.5 2 ml/kg/hr infant 1 ml/kg/hr child 0.5 ml/kg/hr adult Average urine output: 30-50ml/hr
What is the normal range for ALT and it’s function?
275-295
Measures the wt of a solution
Indicator of hydration status