Lab Practical 1 Flashcards
Anatomical position
Point of reference; universally accepted standard position
- Arms by side, palms forward, feet slightly apart, head and toes pointed forward
The thumbs are ____ to the pinky finger
Lateral
Superior
Closer to head
Inferior
Closer to feet
Example of superior/inferior
Ribs are superior to the pelvis
Anterior
Front of the body; portion of the body that leads when walking
Posterior
Back of the body; Portion of the body that trails when walking
Ventral
Bellyside
Dorsal
Backside
In humans, what is equal to anterior
Ventral
In humans, what is equal to posterior
Dorsal
In 4 legged animals, what is equal to anterior
Superior
In 4 legged animals, what is equal to posterior
Inferior
Cranial
Closer to skull
Caudal
Further away from skull
Medial
Closer to midline
Lateral
Further from midline
Example of medial/laterl
Sternum is medial to arms
Proximal
Closer to point of attachment
Distal
Further from point of attachment
When is proximal and distal used
For limbs
Superficial
On the outside of the body
Deep
Closer to the inside
Examples of superficial/deep
Epidermis (skin) is the most superficial part of the body
Organs are deep to the skin
Plane
An imaginary line that runs throughout the body
3 Planes
- Frontal
- Sagittal
- Transverse
Frontal plane
Divides body into anterior and posterior parts
Sagittal plane
Divides body into a right and left part
Transverse plane
Divides body into superior and inferior parts (top and bottom)
Midsagittal
Line that goes directly in middle and makes a perfect right and left (equal)
Section
Cut through an imaginary plane
Viscera
Organs
Serous membranes
Surrounds body cavities
Functions of serous membrane
- Holds organs in place
2. Reduces friction so that organs move smoothly against each other
Parietal membrane
Lines the inside of the cavity
Visceral membrane
Lines the organ
Body cavities
- Dorsal cavity
2. Ventral cavity
Dorsal cavities
- Cranial cavity: Holds the brain
2. Spinal cavity: Holds the spine
Ventral cavities
- Thoracic cavity
2. Abdominopelvic cavity
Peri means
Around
Thoracic cavities
- Pericardial cavities: Holds the heart
2. Pleural cavities: Holds the lungs
What do the pleural cavities look like
There are two pleural cavities, a right and left cavity, one for each lung
Why are the lungs in separate compartments?
For protection, one can collapse and the other will still be healthy and functioning (same with testes)
What separates the thoracic and abdominopelvic cavities
The diaphragm
Abdominopelvic is separated into:
- Abdominal
2. Pelvic: Includes reproductive system
Tissue
Collections of cells and cell products that perform specific, limited function
Type of tissues
- Epithelial tissue
- Connective tissue
- Muscle tissue
- Neural tissue
Functions of epithelial tissue
- Provides physical protection
- Controls permeability
- It only lets specific things in and out
- Ex. Skin lets out sweat and oil, keeps out viruses - Provides sensation
- Sensory neurons allow us to feel - Produce specialized secretions (glandulas epithelium)
Characteristics of epithelial cells
- Cellularity (cell junctions)
- The cells sit really close to each other, which is a defining quality about epithelial tissue - Polarity (apical and basal surfaces)
- Attachment (basement membrane or basal lamina)
- Avascularity
- Regeneration
Polarity
Comparing one side of a cell to the other (top and bottom)
Basement tissue
Provides the cell with something to attach to
Basolateral side
The side of an epithelial cell that is attached to the basement tissue
Apical side
The side of the epithelial cell that is not attached to the basement tissue, this side is always exposed to an open area
Avascularity
Without vasculature/has no blood supply or blood vessels
How do epithelial cells get their nutrients?
From the connective tissue
Why do we need epithelial cells to regenerate?
So that wounds can heal
Stem cells
All epithelial cells have these pods of cells that help regenerate epithelial cells
What do proteins do for cells
Proteins attach two cells together
Types of proteins that hold epithelial cells together
- Tight junctions
- Gap junctions
- Hemidesmosomes
Tight junctions
Holds two cell membranes together that are adjacent, or right next, to each other. Nothing can pass through the plasma membrane of the cells
Gap junction
Leave gaps between the two cells and allows cells next to each other to communicate and pass things back and forth
Hemidesmosomes
The attachment to the deeper connective tissue, this keeps skin from just ripping off
Classifications of Epithelial Cells
- Squamous: Flat, flat nucleus
- Cuboidal: Cube-like, round nucleus
- Columnar: Column-like, stretched nucleus
Simple
One layer
Stratified
More than one layer
All cells on the basal lateral side look like
Stratified cuboidal
What do you look at to tell what type of epithelial cell it is
The cells on the apical side and the nucleus
Simple Squamous Epithelium location
Kidney tubules, lungs (for fast and easy gas exchange)
Simple Squamous Epithelium function
Reduces friction
What does Simple Squamous Epithelium look like
Cobblestone
Why is simple squamous used in capillaries
Because capillaries need fast transport, so simple squamous epithelium is used for easier diffusion because they are thin and flat
Stratified Squamous Epithelium
location
Skin, lining of mouth, throat, anus, and vagina
Stratified Squamous Epithelium function
Protection against abrasion and pathogens
What determines the thickness of the stratified squamous epithelium
How much protection is needed or how much stress is put on that area
Keratin
Protein that can be made by epithelial tissue to give it extra strength. This is made in response to how much stress is on that area and can be used to waterproof, making things not get absorbed as much
Simple Cuboidal Epithelium location
Glands, ducts, kidney tubules, thyroid gland
Simple Cuboidal Epithelium function
Not much protection, but good for secretion and absorption
Secretion
Cell is making something and pushing it outside
Absorption
Cell needs something outside, so it pulls it in
Stratified Cuboidal Epithelium location
Lining of ducts (salivary and sweat glands), rare
Stratified Cuboidal Epithelium function
Protection, secretion, absorption
- Usually only 2-3 layers
Simple Columnar Epithelium location
Lining of stomach, intestine, and collecting ducts of the kidney
Simple Columnar Epithelium function
Really good protection, secretion, and absorption
How to tell if its simple columnar
If the nuclei are in a straight line and on the same level
Goblet cell
Mucus producing cells
Stratified Columnar Epithelium
location
Ducts; mammary glands, salivary gland ducts, and urethra and anus
Stratified Columnar Epithelium
function
Protection, but not as good as simple columnar
Lumen
The area inside the tube like structure of glands, when cut horizontally, looks like a ring, when cut laterally, looks like two separated cells
Pseudostratified Ciliated Columnar Epithelium location
Lining of nasal cavity, trachea, bronchi, male and female reproductive systems
Pseudostratified Ciliated Columnar Epithelium function
Protection, secretion, moves mucus with cilia
What is the difference between pseudostratified ciliated columnar and stratified columnar?
Every single cell is attached to the basement membrane in pseudostratified ciliated, but their nuclei are positioned in different places
Cilia are there to
Move things like eggs and sperm
Goblet cells help the cilia
Move mucus
Transitional Epithelium location
Urinary bladder, renal pelvis, ureters
Transitional Epithelium function
Permits expansion and recoil after stretching
How is transitional epithelium different from the rest?
It can expand
Two forms of transitional epithelium
- Full bladder: Looks like stratified squamous; stretched
2. Empty bladder: Has “umbrella cells” that are expanded; relaxed
Connective tissue
Connects epithelial tissue to everything else
Characteristics of Connective tissue
- Specialized cells (doesn’t make up much of the tissue)
- Solid extracellular protein fibers
- Fluid extracellular ground substance
Matrix
Everything beside the cells; majority of tissue volume; determines specialized function
Matrix is made up of
- Proteins
2. Ground substance (liquid component)
Types of proteins in connective tissues
- Collagen
- Elastic fiber
- Reticular fiber
Collagen
Gives strength, almost always stains with a pink color; long strands
Elastic fiber
Has the ability to stretch; makes the tissue more flexible; long thin strands; stain dark purple or black
Reticular fiber
Stains dark purple or black; has web-like networks; provides strength and support
All tissues have all of these fibers/proteins but…
In different amounts
Classification of connective tissues
- Connective tissue proper
- Connect and protect - Fluid connective tissue
- Transport - Supporting connective tissue
- Structural strength
What cell types are found in connective tissue proper?
- Fibroblasts
- Fibrocytes
- Adipocytes
- Mesenchymal cells
- Macrophages
- Mast cells
- Lymphocytes
- Microphages
- Melanocytes
Types of connective tissue proper
- Loose connective tissue proper
2. Dense connective tissue proper
Types of loose connective tissue proper
- Areolar connective tissue
- Adipose connective tissue
- Reticular connective tissue
Areolar connective tissue function
It distorts without damaging
Areolar connective tissue location
Basement membrane
Areolar connective tissue characteristics
- Flexible, strong, not many cells
- The basement membrane and the dermis is areolar tissue
- Has collagen that goes in all directions (planes) so it can take stress from all directions
- Has a lot of matrix and open space, looks disorganized
Adipose connective tissue (fat) function
Retains body heat, stores energy, and provides protection (cushions), stores triglycerides
Adipose connective tissue location
Buttocks, breasts, around kidneys and eyes
Adipose connective tissue characteristics
- Circular-regions with nuclei
2. Adipocytes
Adipocyte
The big cells in adipose
Reticular connective tissue function
Provides support and framework
Reticular connective tissue location
Bone marrow, spleen, lymph nodes
Reticular connective tissue characteristics
- Predominant protein is the reticular proteins/fiber
- Has a lot of nuclei
- Branching and web-like
- Dark stained fibers
- Predominant protein is the reticular proteins/fiber
Types of dense connective tissue proper
- Dense regular connective tissue
- Dense irregular connective tissue
- Dense elastic connective tissue
Dense regular connective tissue function
Strength in one plane
Dense regular connective tissue location
Tendons and ligaments
Dense regular connective tissue characteristics
- Pink, which means there’s a lot of collagen
- Collagen is organized in the same plane
- Has many fibroblasts: Found in collagen, long and wavy nuclei
Dense irregular connective tissue function
Strength in different planes
Dense irregular connective tissue location
Capsules of organs and dermis
Dense irregular connective tissue characteristics
- Collagen is organized in different planes
- Capsule: Made by dense irregular connective tissue; surrounds our organs
- Preferred to make capsules because it can stretch in all directions
Dense elastic connective tissue function
Stretches and recoils to cushion shocks
Dense elastic connective tissue location
The walls of arteries, between vertebrae of the spinal column
Dense elastic connective tissue characteristics
- Black stain because has elastic proteins
- Stretches in one plane
- Just like dense regular, but with elastic proteins instead of collagen
- Recoils after being stretched
- Wavy when it isn’t stretched
Fluid connective tissues
Blood
Blood has
Lots of erythrocytes
Erythrocytes
Small pink cells, carries oxygen and some carbon dioxide; makes up almost all of the cells in blood; doesn’t have a nuclei
All of the other cells in blood are
Immune cells that are purple because they have a nucleus
What does blood not have a lot of
White blood cells
Supporting Connective Tissue
- Cartilage
2. Bone (osseous tissue)
Types of cartilage
- Hyaline cartilage
- Elastic cartilage
- Fibrocartilage
Hyaline cartilage function
Reduces friction
Hyaline cartilage location
In between bones, in joints
Hyaline cartilage characteristics
- Most common
- Matrix is made of collagen
- Has an even pink color; not in strands
Chondrocytes
Found in cartilage tissue; makes a ton of cartilage and gets trapped in a lacuna, then they divide in the lacuna and pack themselves in
Elastic cartilage function
Flexibility without damage
Elastic cartilage location
External ear and auditory canal
Elastic cartilage characteristics
- Matrix is made of elastic fibers
2. Matrix is dark purple or black
Fibrocartilage function
Good at resisting compression
Fibrocartilage location
Vertebral column between each vertebrae, pads within knee joints
Fibrocartilage characteristics
- Matrix is made of collagen that is bundled up, which adds strength
Osseus Tissue (Bone)
Has a circular structure
Osteon
The whole circular structure
Central canal
Provides blood vessels that provides nutrients
Osteocytes
Cells that make bone and live in lacuna, but there is never more than one
Muscle tissue does what
Contracts in order to generate force
Muscle types
- Skeletal muscle
- Smooth muscle
- Cardiac muscle
Skeletal muscle location
Attached to skeleton
Skeletal muscle function
Moves the skeleton
Summary of skeletal muscle
Voluntary, striated muscle
Muscle fiber
One long tube-like muscle cell that has long cylindrical nuclei on the plasma membrane
Striations/Striated
Long lines in one plane up and down
Muscle cells can/cannot divide
Cannot divide
Stem cells in muscle
Pool of cells that divide in the muscle cells and repair damage
Smooth muscle location
Lines hollow organs and tubes (Ex. Esophagus, digestive tract)
Smooth muscle function
Contract in order to generate force
Summary of smooth muscle
Involuntary, not striated muscle
Smooth muscle can/cannot divide
Can divide
The pink in smooth muscle is not
Collagen
Difference between smooth muscle and dense irregular
There are a lot more nuclei in smooth muscle
Cardiac muscle location
Heart
Cardiac muscle function
Contracts to generate force that moves blood
Summary of cardiac muscle
Involuntary, striated (just like skeletal)
Difference between cardiac and skeletal muscle
Cardiac is branched with forks, which helps it wrap around the heart, and has intercalated discs
Intercalated discs
Dark bands across the fiber; this is where two muscle cells come together; these discs are bundles of gap junctions
What do the gap junctions in the intercalated discs do?
They allow the fibers to communicate so that they will contract at the same time
Neural Tissue function
Communication
How do neural tissues communicate?
Electrical signals/chargers that travel from cell to cell
Cells in neural tissue
- Neurons
2. Neuroglio
Neurons
Cells in neural tissue
Dendrites
Senses the environment, if they receive a stimulus that is strong enough then it sends a signal through the axon
Axon
The electrical signal is sent through this
Neuroglia function
Supports and makes sure that everything is perfect for neurons
Neurons is one of the…
Longest cells in our body