Lab Exam Flashcards
Basophils are indicative of

Parasitic infections

Microcyte

Granulocytic Leukemia
Serum (red top) tubes contain
Nothing
________________________________
Dont need to worry about contaminating other tubes
Urinalysis finding

Fatty Casts

Mott Cells
_________________________
Bone marrow biopsy
Calcium carbonate crystal significance
Normal in horses, rabbits, guinea pigs and goats
Hypochromasia is indicative of
Decreased concentration of Hemoglobin - Iron Deficiency
Urinalysis finding

Epithelial Casts
Urinalysis finding

Bilirubin Crystals
Basophilic stippling in animals other than ruminants is indicative of
Regenerative Anemia
Lead Poisoning (if significant number)
Urinalysis finding

Calcium oxalate dihydrate
Heparin (green top) tubes are used for
Biochemical Profile
Urinalysis finding

Transitional Epithelial Cells

Schistocytes
Neutrophil “Toxic Change” is indicative of
Inflammation - decreased bone marrow transit time
Differential diagnosis for decreased M:E ratio
Regenerative Anemia
Erythroid leukemia
Lack of production of neutrophils
Red blood cell abnormality caused by abnormal aggregation of ribosomes
Basophilic stippling

Basophilic Stippling
Struvite crystals are indicative of
Urease-Positive bacteria formation
Urinalysis finding

Dirofilaria immitis
Functions of monocytes

Phagocytosis
Antigen Presentation
Iron Storage and Recycling
Cytokine Production
Urinalysis finding

Squamous Epithelial Cells
How do you differentiate between rouleaux and agglutination?
Add isotonic saline to a drop of blood - if rouleaux the RBCs will disperse

Lysosomal Storage Disorder
Neutrophils are indicative of

Inflammation

Osteoblasts
______________________
Bone marrow biopsy
Urinalysis finding

Granular Cast
Urinalysis finding

Fungal Hyphae
Urinalysis finding

Struvite Crystals
Eosinophils are indicative of

Allergic disease
Modulate inflammatory response
Phagocytosis
Helminthic parasites
Differential diagnosis for heinz bodies in sheep
Copper toxicosis

Spherocytes
Urinalysis finding

Drug Associated Crystals
Acanthocytes are indicative of
Hepatic Lipidosis = Cats
Hemangiosarcoma = Dogs
Red Blood Cell Parasite

Mycoplasma haemofelis

Acanthocytes
Urinalysis finding

Renal Tubular Epithelial Cells

Basophils
Ammonium biurate crystals are indicative of
Liver disease
__________________________
Normal finding in Dalmations and Bulldogs

Rouleaux Formation
EDTA (purple top) tubes are used for
CBC
Waxy casts are indicative of
Chronic Renal Disease
Urinalysis finding

White Blood Cells
Urinalysis finding

Red blood cells
Urinalysis finding

Yeast - Candida spp
Red Blood Cell Parasite

Anaplasma marginale
Red blood cell abnormality caused by oxidatively denatured Hg
Heinz body formation
Schistocytes are indicative of

Intravascular trauma
Iron Deficiency Anemia
Reticulocyte count of greater than 60,000 uL is indicative of
Regenerative Anemia
Urinalysis finding

Red Blood Cell Cast

Agglutination

Neutrophil Hypersegmentation
Urinalysis finding

Calcium Carbonate Crystals
Urinalysis finding

Caudate Cells

Red Cell Leukemia (Erythremic myelosis)
Serum (red top) tubes are used for
Obtaining serum from the formed clot
Urinalysis finding

Capillaria plica
Reticulate count below 60,000 uL is indicative of
Non-Regenerative to poorly regenerative anemia

Macrophages
____________________
Bone marrow biopsy
What are the two types of RBC’s pictured?

Polychromatic and Hypochromatic cells
_______________________________
Polychromatic = blueish colored
Hypochromatic = increased central pallor

Stomocytes
Urinalysis finding

Hyaline Cast
Calcium oxalate dihydrate crystals suggest
Storage artifact
Calcium oxalate urolithiasis
Increased calcium excretion due to hypercalcemia
Acute renal failure
_________________________________
Can be normal
Epithelial casts and fatty casts are indicative of
Tubular degeneration and necrosis
Renal Ischemia
Toxic nephrosis
Agglutination of RBC is indicative of

Antibody attachement to RBCs (IMHA)
Howell Jolly Bodies are indicative of
Regenerative Anemia
Non Functioning Spleens (Splenectomy)
Increased Corticosteroid Use
Lead Poisoning
Spherocytes are indicative of

IMHA
Differential diagnosis for heinz bodies in cattle
Ingestion of Kale
Ingestion of onions
Parasite seen in bone marrow biopsy

Toxoplasmosis
Differential diagnosis for heinz bodies in equines
Phenothiazines
Ingestion of wilted red maple leaves

Birman Cat Neutrophil Granulation Anomaly

Mast Cells
_____________________________
Bone Marrow biopsy
Parasite seen in bone marrow biopsy

Leishmania
Citrate (blue top) blood tubes contain
Anti-Coagulant

Leukemia
Sodium Fluoride (grey top) tubes are used for
Glucose/Lactate Measurement
Basophlic stippling is normal in what species
Ruminants
Reticulocyte count below 10,000uL is indicative of
Non Regenerative Anemia
Eccentrocytes are indicative of

Oxadative damage (Onion ingestion)
_________________________________
Often seen in conjuction with Heinz Body formation
Echinocytes are indicative of

Crenation artifact d/t slow drying
Electrolyte imbalances
Non-specific disease (kidney disease)
Rattlesnake envenomation
Urinalysis finding

Ammonium Biurate Crystals
Differential diagnosis for increased M:E ratio
Erythroid Hypolasia/Aplasia
Granulocytic Hyperplasia
Granulocytic Leukemia
What stains are used to detect heinz bodies?
Wrights Stain
New Methylene Blue Stain

Keratocyte

Megakaryoblastic Leukemia
Citrate (blue top) tubes are used for
Individual factor analysis
Coagulation panel
Red Blood Cell Parasite

Babesia gibsoni
Normal Myeloid : Erythroid Ratio
1:1 up to 3:1
Calcium oxalate monohydrate crystals are indicative of
Oxalate urolithiasis
Hypercalciuric or hyperoxaluric disorders
Ethylene toxicosis
___________________________________________
Can be seen in healthy animals
Differential diagnosis for heniz bodies in dogs
Cephalosporins
Zn toxicosis
Onion ingestion
Rouleax formation is indicative of

Horses - normal
Small Animals - increased globulin

Lymphocyte

Echinocytes
Urinalysis finding

Red Blood Cell Parasite

Cytauxzoon felis

Heinz Bodies

Leptocytes and Codocytes
Urinalysis finding

Calcium Oxalate Monohydrate
Red Blood Cell Parasite

Babesia canis
Red blood cell casts are indicative of
Tubular hemorrhage
Urinalysis finding

Amorphus Crystals
Basophils contain

Histamine
Heparin
Proteins
Microcytes are indicative of
Iron Deficiency Anemia

Macrocyte
Parasite seen in bone marrow biopsy

Histoplasmosis

Chediak-Higashi Syndrome

Eosinophils

Neutrophil “Toxic” Change
Significance of stomocytes

Few are normal and insignificant
Hereditary stomocytosis (Alaskan Malamutes, Min Schnauzers, Drentse partrijshond)
Neutrophil hypersegmentation is indicative of

Aging Change
Glucocorticoid usage
Hyperadrenal disease
Stress
Cystine crystals are indicative of

Eccentrocytes
Urinalysis finding

Cystine Crystals
Hyaline casts are indicative of
White blood cell casts are indicative of
Tubular inflammation

Osteoclast
__________________________
Bone Marrow Biopsy
Red Blood Cell Parasite

Mycoplasma wenyoni

Plasma cells
____________________
Bone Marrow biopsy
What stain is used to visualize reticulocytes

New Methylene Blue
Brilliant Cresyl Blue
Polychromasia is indicative of

Blood loss
Blood destruction
Keratocytes are indicative of

Iron deficiency

Distemper Viral Inclusion Body
Condition caused by inherited neutrophil abnormality

Birman Cat Neutrophil Granulation Anomaly

Neutrophil

Nucleated RBCs
Howel Jolly Bodies
Red Blood Cell Parasite

Mycoplasma haemocanis

Pelger-Huet Anomaly
___________________________
Neutrophils all look like bands
Differential diagnosis for heinz bodies in cats
Acetaminophen
Propylene glycol
Lymphoma
Hyperthyroidism
Diabetes

Monocyte

Reticulocytes
Macrocytes are indicative of

Regenerative Anemia
Urinalysis finding
