Lab: Blood Flashcards

1
Q

what percentage of plasma is proteins and what are they?

A

9%
albumin
fibrinogen
transport proteins
clotting proteins
immune proteins (antibodies)

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2
Q

what are the formed elements in blood

A

erythroytes

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3
Q

what is the buffy coat in a blood sample made of

A

platelets
leukocytes

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4
Q

describe the shape of an erythrocyte

A

biconcave shape

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5
Q

which type of cell has no nucleus or organelles

A

erythrocytes

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6
Q

what do erythrocytes do

A

carry O2 and CO2, contain millions of hemoglobin molecules

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7
Q

which leukocytes are granulocytes

A

neutrophils
eosinophils
basophils

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8
Q

describe what neutrophils do

A

phagocytes that ingest and destroy bacterial cells using granule contents

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9
Q

what percentage of leukocytes are neutrophils

A

60%

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10
Q

describe the function of eosinophils

A

respond to infections with parasitic worms
mediates allergic response

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11
Q

what percentage of leukocytes are eosinophils

A

3%

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12
Q

describe the function of basophils

A

chemicals in granules mediate inflammation

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13
Q

what percentage of leukocytes are basophils

A

less than 1%

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14
Q

what are the agranulocytes

A

lymphocytes and monocytes

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15
Q

name the 2 types of lymphocytes and what they do

A

both are activated by antigens
B lymphocytes: produce antibodies which bind to and remove antigens from tissues
T lymphocytes: activate other immune system components and directly destroy abnormal body cells

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16
Q

what percentage of leukocytes are lymphocytes

A

30-34%

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17
Q

describe the function of monocytes/macrophages

A

exit capillaries to enter tissues where some mature into macrophages
macrophages are phagocytic cells that ingest dead and dying cells, bacteria, antigens, etc.

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18
Q

what percentage of leukocytes are monocytes/macrophages

A

4-8%

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19
Q

what is the final common pathway of hemostasis

A

prothrombin–>thrombin–>fibrinogen–>fibrin (in actuality plasminogen–>plasmin desolving the fibrin clot is the last step, but whatever ignore this)

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20
Q

what antigen is present in Type A blood

A

only A antigen is present on erythrocytes

21
Q

what antigen is present in Type B blood

A

only B antigen is present on erythrocytes

22
Q

what antigen is present in Type AB blood

A

both A and B antigens are present on erythrocytes

23
Q

what antigen is present in Type O blood

A

neither A or B antigens are present on erythrocytes

24
Q

what antibodies are present in Type A blood

A

only anti-B antibodies are present in plasma

25
what antibodies are present in Type B blood
only anti-A antibodies are present in plasma
26
what antibodies are present in Type AB blood
No antibodies are present in plasma
27
what antibodies are present in Type O blood
both anti- A and anti-B antibodies are present in plasma
28
Rh+ and Rh- means..
Rh antigen or not on erythrocytes leading there to be 8 different common blood types
29
what is the universal donor and why
O- (Type O without Rh antigen) because erythrocytes do not have A, B, nor Rh surface antigens
30
what is the universal recipient and why
AB+ (Type AB with Rh antigen) because these individuals do not make antibodies to A, B, or Rh antigens
31
where do platelets come from
megakaryocytes
32
what are megakaryocytes
cells keep going through mitosis but not cytokinesis (giant cells with a bunch of DNA)
33
name the leukocytes in order of most abundant to least abundant in the blood
neutrophils, lymphocytes, monocytes, eosinophils, basophils (Never Let Molly Eat Bagels)
34
what is hematocrit and what does it show pathologically
measures the percentage of erythrocytes in whole blood shows anemia (too little RBCs for blood volume) or polycythemia (too many RBCs for blood volume)
35
what is the equation that determines hematocrit
hematocrit= (length of erythrocytes/length of whole blood) * 100
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