lab 1: cell maturation Flashcards
what gives RBC’s their color
hemoglobin
define polychromatic
many colors
what does central pallor mean
clear or pale center
what is deep blue cytoplasm known as
basophilic
describe color change as RBC’S mature
blue-purple-red
define anemia
lack of RBC’S in the blood
what is hematopoiesis
production of all RBC’S including platelets
hormone produced by kidney during hypoxia
EPO
what does EPO stand for
erythropoietin
another name for stem cell
progenitor
what is PPSC
common ancestor cell
what does PPSC stand for
pluripotent stem cell
what is the % of prorubricytes in bone marrow
3-4%
what is the % of metarubricytes in bone marrow
57%
what is the % of rubriblasts in bone marrow
35%
where are RBC’S produced in an adult
bone marrow
where are RBC’S produced in the fetus
spleen and liver
what are the 2 types of bone marrow
red and yellow
why does the bone marrow change color
more fat cells during ages causes the yellow bone marrow
what do mature RBC’S lack
nucleus
why do RBC’S have a central pallor
they are a bi-concave disk
nucleus vs cytoplasm ratio in a rubriblast
7:1
when are reticulocytes seen in blood
regenerative anemia
4 things that change as RBC’S mature
size, color, looses nucleus, chromatin clumps
when is the nucleolus present
rubriblast
what stage has a peri nuclear clear zone
prorubricyte
which stage is NRBC
metarubricytes
what is an NRBC
nucleated red blood cell
mast immature RBC
rubriblast
how is a rubriblast recognized
nucleolus
what cells are seen in loss or distraction of RBC
metarubricytes
what RBC stage can start carrying oxygen
reticulocytes
