immunology and serology Flashcards
Two main categories of immunology
Innate and acquired
Define immunology
Study of bodies mechanisms that discriminate between self and non self; also eliminating non self agents
Define self
Supposed to be there
Define non self
Foreign body
Another name for innate
Passive, biological, non specific
What makes up the lymphatic system
Bone marrow, spleen, thymus
Define antigen
Foreign substance
Define Pathogen
Microorganism that can cause disease
T or F: Innate immunity has no memory
True
How quickly does innate immunity respond
Within minutes to hours
Name the 3 innate defenses
Anatomical barriers, inflammation, resident flora
What is the #1 line of defense
Skin
What type of bacteria do antibiotics remove
Both good and bad
What are the 4 innate defenses cellular components
Neutrophils, macrophages, natural and lymphokine killers, eosinophil
What is the purpose of neutrophils
Dilate blood vessels and allow blood into tissues
What do natural killers do
Kill viruses
What do lymphokine killers do
Kill tumor cells
What is the component system
Group of proteins in the blood; innate and adaptive
What are the 2 types of acquired immunity
Humoral and cell mediated
Define humoral immunity
Antibody-mediated immune response; active or passive
Define active humoral immunity
Body producing an antibody after exposure to a foreign antigen
Define passive humoral immunity
Passage of antibody that has been produced by one animal to another
Where are antibodies formed
Bone marrow
What are antibodies considered
Proteins
What do plasma cells produce
Immunoglobulins
What do T-cells produce
Cytokines that stimulate B-cells
What are plasma cells also known as
Effector cells
What do plasma cells attach to
Free floating pathogens
What do plasma cells secrete
Antigen specific antibodies
What does a cell mediated immune system involve
T-cells and phagocytes
MCH
Major histocompatability complex
