L80: Reproduction 2 Flashcards
Seminal vesicles secrete
prostaglandins - stimulate uterine/fallopian tube contractions
Prostate gland secretes
alkaline secretions
In what accessory gland do sperm gain motility and lose cytoplasm? And is a reservoir for sperm? Stabilize acrosome?
Epididymis
Which of the following gonadal hormones is NOT a negative inhibitor of the pituitary?
A. Activin
B. Inhibitin
C. Follistatin
D. Testosterone/Estrogen
A. Activin
Which does NOT negatively feedback on hypothalamus?
A. Inhibin
B. Testosterone/Estrogen
C. Dopamine/Endorphins
D. Norepinephrine
D. NE
Which of the following PROMOTES release of LH and FSH?
A. Inhibin
B. Dopamine/Endorphins
C. Testosterone/Estrogen
D. Continuous exposure to GnRH
E. Pulsatile exposure to GnRH
E.
Whats the major regulator of FSH?
inhibin
What’s the major regulator of LH?
Testosterone
What does corpus luteum secrete?
Progesterone
Whats an acrosome on a spermocyte?
“A cap of membranes containing digestive enzymes”
Estradiol is carried by what binding protein?
SHBG
Progesterone is transported in blood by what carrier protein?
CBG
What is the most hydrophilic hormone on this table?
Androstendione
What is the most hydrophobic hormone on this table?
Dihydrotestosterone
what mechanism keeps the testes at the right temperature
counter-current heat exchange
What stage of spermatogenesis, does the acrosome form?
Spermiogenesis
Formation of residual body occurs in what stage of spermatogenesis?
Spermeation
During spermiogenesis, developing sperm are attached to the sertoli cell via
tight junction
Gametes are immunologically distinct from parent. It is protected from the parent immune system via
tight junctional border in testes
Prostaglandins, secreted from the seminal vesicles, promote
contraction of the uterus and fallopian tubes.
bodybuilders coming off steroids take
hCG
If spermatogenesis is TOO FAST, the developing germ cell release signals to Sertoli, which increase release of _____
inhibin which negatively regulates ant. pituitary release of FSH
If spermatogenesis is too slow, then sertoli cells secrete less ___________ which releases suppression of ant. pituitary to secrete _______
inhibin, FSH
NO stimulates _________, producing cGMP that leads to vasodilation
guanylyl cyclase
Which vein collapses during erection, preventing blood outflow?
Superficial dorsal vein
Emission is under control of
sympathetic spinal reflex
give me an example of hypogonadotrophic hypogonadism
hyperprolactinemia (strong negative feedback of prolactin on hypothalamus)
give me 3 examples of incomplete androgen insensitivity
A. Testosterone receptor defect
B. Testosterone pathway defect
C. 5-alpha reductase deficiency
zona pellucida
“egg shell” made of mucopolysaccharide immediately around oocyte formed by granulosa cells
cumulus oophorus
granulosa cell that docks oocyte to wall of follicle
How does the graafian follicle grow?
Antral fluid increases as mucopolysaccharides depolymerize and pull water
How does the oocyte move into fallopian tubes
fimbrae sweep it in
corpus luteum secretes
progesterone
if fertilization doesnt occur
luteolysis
main action of activin
stimulates FSH release
Which inhibin is from the dominant graafian follicle?
inhibin B
What inhibin is from the corpus luteum?
inhibin A
What is the rate limiting step in ovarian steroid biosynthesis
Cholesterol to pregnenalone via desmolase
What is E1
estrone
What is E2
Estradiol (dominant estrogen)
