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FHB - Endocrinology (by Richie) > L80: Reproduction 2 > Flashcards

L80: Reproduction 2 Flashcards

1
Q

Seminal vesicles secrete

A

prostaglandins - stimulate uterine/fallopian tube contractions

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2
Q

Prostate gland secretes

A

alkaline secretions

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3
Q

In what accessory gland do sperm gain motility and lose cytoplasm? And is a reservoir for sperm? Stabilize acrosome?

A

Epididymis

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4
Q

Which of the following gonadal hormones is NOT a negative inhibitor of the pituitary?

A. Activin

B. Inhibitin

C. Follistatin

D. Testosterone/Estrogen

A

A. Activin

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5
Q

Which does NOT negatively feedback on hypothalamus?

A. Inhibin

B. Testosterone/Estrogen

C. Dopamine/Endorphins

D. Norepinephrine

A

D. NE

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6
Q

Which of the following PROMOTES release of LH and FSH?

A. Inhibin

B. Dopamine/Endorphins

C. Testosterone/Estrogen

D. Continuous exposure to GnRH

E. Pulsatile exposure to GnRH

A

E.

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7
Q

Whats the major regulator of FSH?

A

inhibin

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8
Q

What’s the major regulator of LH?

A

Testosterone

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9
Q

What does corpus luteum secrete?

A

Progesterone

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10
Q

Whats an acrosome on a spermocyte?

A

“A cap of membranes containing digestive enzymes”

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11
Q

Estradiol is carried by what binding protein?

A

SHBG

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12
Q

Progesterone is transported in blood by what carrier protein?

A

CBG

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13
Q

What is the most hydrophilic hormone on this table?

A

Androstendione

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14
Q

What is the most hydrophobic hormone on this table?

A

Dihydrotestosterone

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15
Q

what mechanism keeps the testes at the right temperature

A

counter-current heat exchange

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16
Q

What stage of spermatogenesis, does the acrosome form?

A

Spermiogenesis

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17
Q

Formation of residual body occurs in what stage of spermatogenesis?

A

Spermeation

18
Q

During spermiogenesis, developing sperm are attached to the sertoli cell via

A

tight junction

19
Q

Gametes are immunologically distinct from parent. It is protected from the parent immune system via

A

tight junctional border in testes

20
Q

Prostaglandins, secreted from the seminal vesicles, promote

A

contraction of the uterus and fallopian tubes.

21
Q

bodybuilders coming off steroids take

A

hCG

22
Q

If spermatogenesis is TOO FAST, the developing germ cell release signals to Sertoli, which increase release of _____

A

inhibin which negatively regulates ant. pituitary release of FSH

23
Q

If spermatogenesis is too slow, then sertoli cells secrete less ___________ which releases suppression of ant. pituitary to secrete _______

A

inhibin, FSH

24
Q

NO stimulates _________, producing cGMP that leads to vasodilation

A

guanylyl cyclase

25
Q

Which vein collapses during erection, preventing blood outflow?

A

Superficial dorsal vein

26
Q

Emission is under control of

A

sympathetic spinal reflex

27
Q

give me an example of hypogonadotrophic hypogonadism

A

hyperprolactinemia (strong negative feedback of prolactin on hypothalamus)

28
Q

give me 3 examples of incomplete androgen insensitivity

A

A. Testosterone receptor defect

B. Testosterone pathway defect

C. 5-alpha reductase deficiency

29
Q

zona pellucida

A

“egg shell” made of mucopolysaccharide immediately around oocyte formed by granulosa cells

30
Q

cumulus oophorus

A

granulosa cell that docks oocyte to wall of follicle

31
Q

How does the graafian follicle grow?

A

Antral fluid increases as mucopolysaccharides depolymerize and pull water

32
Q

How does the oocyte move into fallopian tubes

A

fimbrae sweep it in

33
Q

corpus luteum secretes

A

progesterone

34
Q

if fertilization doesnt occur

A

luteolysis

35
Q

main action of activin

A

stimulates FSH release

36
Q

Which inhibin is from the dominant graafian follicle?

A

inhibin B

37
Q

What inhibin is from the corpus luteum?

A

inhibin A

38
Q

What is the rate limiting step in ovarian steroid biosynthesis

A

Cholesterol to pregnenalone via desmolase

39
Q

What is E1

A

estrone

40
Q

What is E2

A

Estradiol (dominant estrogen)

FHB - Endocrinology (by Richie) (24 decks)

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