Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

FHB - Endocrinology (by Richie) > L70: Hypothalamic-Pituitary Relationship > Flashcards

L70: Hypothalamic-Pituitary Relationship Flashcards

1
Q

What artery supplies the portal system of the anterior pituitary?

A

Superior hypophyseal artery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Hypothalamic releasing factors all target

A

anterior pituitary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What brain nucleus is dopamine synthesized in?

A

Arcuate nucleus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Table of hypothalamic releasing hormones…

A

See table

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Bonus: how many peptides long is GnRH

A

10aa’s! It is HIGHLY CONSERVED among vertebrates.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Bonus: how many peptides long is TSH?

A

3aa’s only!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What kind of receptor binds GnRH?

A

GPCR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

GnRH neurons fail to cross cribriform plate into CNS during development

A

Kallman’s syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Pulsatility of GnRH mirrors pulsatility of

A

LH release

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

When GnRH pulse rate decreases, what happens to LH and FSH secretion?

A

LH decreases, FSH increases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

The hypothalamic releasing hormone regulates WHAT SUBUNIT of a pituitary glycoprotein hormone?

A

B-subunit varies and is regulated. Alpha-unit is conserved.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

GnRH binds GPCR in a pulsatile manner. Does this promote the synthesis of hormones, or the release of hormones?

A

Both!

IP3/Ca2+ pathway: promotes hormone release

DAG/PKC pathway: promotes hormone synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

The pulsatility of GnRH is significant because

A. It maximizes the availability of the receptor

B. Promotes differential release of hormones

C. Promotes differential synthesis of hormones

D. All of the above

A

D. All of the above

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Neurohypophysial tract

A

Neurons whose axons terminate in the posterior pituitary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which send axons to the median eminence, into capillary system?

A. Tuberoinfundibular system

B. Neurohypophysial tract

A

A.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Histologically, posterior pituitary tissue is derived from

A

Neural tissue derived from neuroectoderm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Histologically, the anterior pituitary is derived from

A

Glandular tissue (epithelial cells) from embryonic foregut (endoderm just fyi)

18
Q

This is the pituitary. The dark cells above are

A

Glandular, thus anterior pituitary (pars distalis)

19
Q

This is the pituitary. The lighter cells below are

A

Neural. Posterior pituitary (pars nervosa)

20
Q

What are magnocellular neurosecretory cells?

A

Cell bodies of the posterior pituitary located in the hypothalamus, that secrete OT, NP, and AVP into the post. pit. capillary bed

21
Q

What is the blood supply for the post. pit?

A. Inf. hypophysial a.

B. Sup. hypophysial a.

A

A. INFERIOR hypophysial a.

22
Q

What are the darkly (purple) stained cells here?

A

Pituicytes - the glial cells of the post. pit

23
Q

What are these red stained bodies?

A

Herring bodies - unmyelinated axon terminals in the posterior pituitary, that originated in magnocellular neurosecretory cells from the neurohypophysis.

24
Q

What’s another word for the anterior pituitary?

A

Adenohypophysis

25
Q

What is the interface for all hypophysiotrophic hormones?

A

Median eminence.

Lies outside the BBB and forms the floor of 3rd ventricle.

26
Q

Dopamine promotes milk production or ejection?

A

Production. Oxytosin promotes milk ejection

27
Q

GnRH. What brain nuclei?

A

POA mostly

28
Q

CRH. What brain nuclei?

A

PVN (parvocellular)

29
Q

TRH. What brain nuclei?

A

PVN

30
Q

GHRH. What brain nucleus?

A

Arcuate nucleus.

(think of a giant doing pullups on the St. Louis Arch)

31
Q

Somatostatin

A

Periventricular nucleus (PeVN) not paraventricular

(think of Katy PERI STOPPING the half-time show)

32
Q

Dopamine. What brain nucleus?

A

Arcuate nucleus

(the giant doing pullups on the St. Louis Arch is high on DOPE)

33
Q

Hormone RELEASE. Is this IP3/Ca2+ or DAG/PKC?

A

IP3/Ca2+

34
Q

What part of FLAT PiG is basophiles?

A

FLAT

35
Q

What part of FLAT PiG is acidophiles?

A

PiG

36
Q

Which are the most numerous cell type in anterior pituitary?

A

Acidophiles (prolactin and GH secreting)

37
Q

Whats a parvicellular neuron

A

Terminates on median eminence, releasing FLAT PiG

38
Q

What is a magnocellular neuron

A

Terminates in neurohypophysis (posterior pituitary) releasing AVP and OT

39
Q

What catecholamine suppresses the release of prolactin?

A

Dopamine

40
Q

What catecholamine suppresses the SYNTHESIS of milk?

A

Dopamine inhibits prolactin, which promotes milk synthesis

41
Q

What 3 parts compose the anterior pituitary?

A

Pars distalis (90%)

Pars intermedia

Pars tuberalis

42
Q

What are the anatomical parts of the posterior pituitary?

A

Pars nervosa

Infundibulum (stalk)

FHB - Endocrinology (by Richie) (24 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions