L6-THE HERP Flashcards

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1
Q

What type of genome is the the Herpesvirus?

A

dsDNA

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2
Q

Is the Herpesvirus enveloped or non enveloped?

A

enveloped (fragile, mucosal transmission)

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3
Q

What is unique about where the Herpesvirus replicates inside the host cell?

A

It does it in the nucleus!

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4
Q

How long to Herpes virus infections typically last?

A

LIFE LONG

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5
Q

What is the Anti-Viral prescribed for Herpes treatment?

A

Acyc-Lovir

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6
Q

The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-1 GO HERPES!!!!

A

HHV-1: Herpes Simplex Virus-1….Neuron…Cold Sore/Oral Ulcers…67%

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7
Q

The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-2 GO HERPES!!!!

A

Herpes Simplex Virus-2….Neuron…GENITAL herpes….15% (more females then males)

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8
Q

The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-3 GO HERPES!!!!

A

Veracella-Zoster-Virus…Neuron…ChickenPox, Shingles….100%

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9
Q

The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-4 GO HERPES!!!!

A

Epstein-Barr Virus….B cells(get it Barr cells)…Infectious Mononucleosis & Burkitt’s Lymphoma…75%

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10
Q

The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-5 GO HERPES!!!!

A

Cytomegalovirus…Lymphocytes, monocytes….Congential Infection….50%

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11
Q

The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-6 GO HERPES!!!!

A

none….Monocytes/Macrophages…Roseola infantum…100%

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12
Q

The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-7 GO HERPES!!!!

A

none…T cells…Roseola Infantum…100%

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13
Q

The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-8 GO HERPES!!!!

A

Kaposi’s Sarcoma Virus…Lymphocytes…Kaposi’s Sarcoma…10%

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14
Q

When a virus is latent inside of the cell where are the 2 places it can chill?

A
  1. integrated in the DNA 2.plasmid
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15
Q

Which viral infection stage is associated with virema? Which one is local?

A

Primary infection=viremia….Secondary infection=local

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16
Q

What is dental related that can elicit a reoccurrence of a herpesvirus infection?

A

Oral Surgery!

17
Q

What % of people that contract HSV-1 are asymptomatic?

A

85% (remember 67% of americans infected)

18
Q

What TYPE of neuron is associated with HSV-1 latency?

A

a sensory ganglia

19
Q

Which herpesvirus’ are associated with mother to fetus if mother is in primary infection during pregnancy?

A

HSV-1, HSV-2,HSV-5

20
Q

Which HSV is associated with herpes Gladatorium?

A

HSV-1

21
Q

How long does it take after sexual contact for a lesion of HSV-2 to appear?

A

about 6 or 7 days

22
Q

What is the only HHV spread via Respiratory Droplets?

A

Veracella-Zoster Virus (HHV-3)

23
Q

Which strains is acyclovir most effective against?

A

HHV-1,2,3

24
Q

What did the Pt with 1/2 of the tongue covered in lesions have going on? How was it treated?

A

HHV-3…Acyclovir

25
Q

Why don’t i have to worry about Burketts Lymphoma?

A

Its in sub-saharan Africa

26
Q

Why is HHV-4 called the Kissing Disease?

A

It has a low viral load so you need to transfer a lot of it ;)

27
Q

What is hyper proliferated in Burkett’s lymphoma? Also, Which area is affected?

A

B-cells….Head and Neck

28
Q

Which HHV is associated with Hairy Leukoplakia?

A

HHV-4

29
Q

Is there a vaccine for HHV-5? Why or why not?

A

NO! multiple strains of cytomegalovirus

30
Q

How much of the third world population is infected with HHV-5? Americans?

A

100% 3rd world…America 50%…

31
Q

What is the current #1 cause of mental retardation?

A

a HHV-5 infection during birth

32
Q

What are the 4 other Oral viruses we discussed?

A

Coxsackie…Measles…Mumps….HPV

33
Q

What is the anti viral geared toward HPV?

A

Gardasil