L6-THE HERP Flashcards
What type of genome is the the Herpesvirus?
dsDNA
Is the Herpesvirus enveloped or non enveloped?
enveloped (fragile, mucosal transmission)
What is unique about where the Herpesvirus replicates inside the host cell?
It does it in the nucleus!
How long to Herpes virus infections typically last?
LIFE LONG
What is the Anti-Viral prescribed for Herpes treatment?
Acyc-Lovir
The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-1 GO HERPES!!!!
HHV-1: Herpes Simplex Virus-1….Neuron…Cold Sore/Oral Ulcers…67%
The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-2 GO HERPES!!!!
Herpes Simplex Virus-2….Neuron…GENITAL herpes….15% (more females then males)
The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-3 GO HERPES!!!!
Veracella-Zoster-Virus…Neuron…ChickenPox, Shingles….100%
The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-4 GO HERPES!!!!
Epstein-Barr Virus….B cells(get it Barr cells)…Infectious Mononucleosis & Burkitt’s Lymphoma…75%
The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-5 GO HERPES!!!!
Cytomegalovirus…Lymphocytes, monocytes….Congential Infection….50%
The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-6 GO HERPES!!!!
none….Monocytes/Macrophages…Roseola infantum…100%
The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-7 GO HERPES!!!!
none…T cells…Roseola Infantum…100%
The HHV table!!! Common Name, Latent in, Important Diseases, and % population infected for: HHV-8 GO HERPES!!!!
Kaposi’s Sarcoma Virus…Lymphocytes…Kaposi’s Sarcoma…10%
When a virus is latent inside of the cell where are the 2 places it can chill?
- integrated in the DNA 2.plasmid
Which viral infection stage is associated with virema? Which one is local?
Primary infection=viremia….Secondary infection=local
What is dental related that can elicit a reoccurrence of a herpesvirus infection?
Oral Surgery!
What % of people that contract HSV-1 are asymptomatic?
85% (remember 67% of americans infected)
What TYPE of neuron is associated with HSV-1 latency?
a sensory ganglia
Which herpesvirus’ are associated with mother to fetus if mother is in primary infection during pregnancy?
HSV-1, HSV-2,HSV-5
Which HSV is associated with herpes Gladatorium?
HSV-1
How long does it take after sexual contact for a lesion of HSV-2 to appear?
about 6 or 7 days
What is the only HHV spread via Respiratory Droplets?
Veracella-Zoster Virus (HHV-3)
Which strains is acyclovir most effective against?
HHV-1,2,3
What did the Pt with 1/2 of the tongue covered in lesions have going on? How was it treated?
HHV-3…Acyclovir
Why don’t i have to worry about Burketts Lymphoma?
Its in sub-saharan Africa
Why is HHV-4 called the Kissing Disease?
It has a low viral load so you need to transfer a lot of it ;)
What is hyper proliferated in Burkett’s lymphoma? Also, Which area is affected?
B-cells….Head and Neck
Which HHV is associated with Hairy Leukoplakia?
HHV-4
Is there a vaccine for HHV-5? Why or why not?
NO! multiple strains of cytomegalovirus
How much of the third world population is infected with HHV-5? Americans?
100% 3rd world…America 50%…
What is the current #1 cause of mental retardation?
a HHV-5 infection during birth
What are the 4 other Oral viruses we discussed?
Coxsackie…Measles…Mumps….HPV
What is the anti viral geared toward HPV?
Gardasil
