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Oral Microbiology!!! > L3-Oral Defense Mechs > Flashcards

L3-Oral Defense Mechs Flashcards

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1
Q

What is unique about the Junctional Epithelium?

A

It is leaky! not like the attached gingiva!

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2
Q

What three things keep fluid in and therefore cause swelling during gingivitis?

A

Keratin layer, lipid layer, and tight junctions

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3
Q

How much more storage of PMNs occurs in the bone marrow then in the blood?

A

5x more PMNs in marrow then blood

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4
Q

What is the PMN half life in blood?

A

6 hours

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5
Q

What are the 6 steps for the PMN to do its thang? What color is the end resulting pus?

A

1.margination 2.emigration 3.chemotaxis 4.phagocytois 5.local release 6.death…viscous green pus

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6
Q

What does CAM stand for?

A

Cell Adhesion Molecule

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7
Q

What is the main antibody in crevicular fluid? Saliva?

A

Crevicular: IgG like the blood…Saliva: IgA

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8
Q

What are the 5 functions of saliva?

A

1.Dissolve food 2.Buffer 3.Lube 4.Pellicle 5. IgA

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9
Q

What is the original source for ‘secreteatory’ component on IgA?

A

The Fc receptor that hooked IgA into the cell

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10
Q

What is sIgA resistant to?

A

Proteases

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11
Q

What is the IgA shape?

A

Dimeric

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12
Q

What are the two Gram - cocci that can metabolize lactic acid?

A

Neisseria and Veillonella Alcalescens

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13
Q

The _________ of the junctional epithelium are poorly differentiated and make little keratin, little hydrophobic granular materials, and are loosely linked to each other. This allows capillary plasma exudate and migrating PMNs to readily pass into the gingival crevice area = ______!

A

keratinocytes….LEAKY

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14
Q

What is PMN half-life in tissue/cells?

A

1-2 days

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15
Q

About 2/3 of blood leukocytes (white blood cells) are _______.

A

PMN’s

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16
Q

How do PMN’s get to the site of infection?

A

A chemotactic trail

17
Q

The fluid defenses of the oral cavity include both ______ and ________ fluid.

A

saliva and crevicular

18
Q

What are 2 examples of non specific antimicrobials in saliva?

A

lysozyme and antimicrobial peptides

19
Q

What are the ___ steps for the production of sIgA’s?

A

Ag binds to a PMN–>PMN shows T-helper–>T-helper tells B cells to proliferate and make IgA–>IgA w/J-chain get taken into endothelial cell by poly-Ig receptor–>IgA comes out as sIgA with the secretory component attached

Oral Microbiology!!! (12 decks)

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