L2-immunology Flashcards

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1
Q

Which immune cells signal acute inflammation?

A

NeutroPhils (QUICKLY NEUTROLIZE THE THREAT!)

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2
Q

Which immune cells signal chronic inflammation?

A

Macrophages(monocytes) (slow to get to the party)

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3
Q

What are the three main bacteria involved in bacterial meningitis?

A

1.Streptoccus Pneumoniae 2. Haemophilus Influenza 3.Neisseria Meningitis

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4
Q

What are the three main features of the innate immune system?

A

1.broad 2.fast 3. no memory

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5
Q

What are the three main features of the adaptive immune system?

A

1.specific 2.slow 3.memory

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6
Q

What are the 3 types of endotoxin?

A

1.Super Antigen 2.Cytolytic 3.A-B Toxin

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7
Q

Which antibodies can cross the placenta?

A

IgE

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8
Q

What is the most antibody made?

A

IgA

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9
Q

What are the response molecules in the first part of inflammation? What are the ‘sentinel’ cells that release them?

A

Histamine released from mast cells

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10
Q

What type of cell is going to show the CAM ‘stop signs’?

A

endothelial cells are going to display the Cell Adhesion Miolecules

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11
Q

What are the receptors present on phagocytes that allow them to grab on to the opsonizied pathogen?

A

Fc receptors

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12
Q

What type of cell releases cytokines?

A

T-cells (T helper cells)

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13
Q

What is the first cell in action to recognize S. Pneumonia?

A

B-cells, they then tell T cells to clone and release cytokines, as well as tell B cells to make antibodies toward that pathogen

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14
Q

What antibody is associated with Type I hypersensitivity?

A

IgE

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15
Q

Which antibodies are associated with Type II hypersensitivity?

A

IgG, IgM

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16
Q

What are the components to hypersensitivity Type III?

A

Antibody-Antigen-Complement System

17
Q

Which is the first made pentamer immunoglobulin?

A

IgM

18
Q

Which immunoglobulin is found in the tissue, blood and can cross the placenta to the fetus?

A

IgG

19
Q

Which immunoglobulin comes through secretions/mucosal surface?

A

sIgA

20
Q

Which immunoglobulin comes from mast cells/basophils/eosinophils?

A

IgE

21
Q

Which immunoglobulin is just involved in B cell activation and is not used further in the immune response?

A

IgD