L1-overview Flashcards
What are the 3 types of Exotoxins?
1.Cytolytic 2.Super Antigen 3.AB
What are the 5 infectious agents to humans?
1.Archea (prokaryote) 2.bacteria (prokaryote) 3.eukaryotes 4.infectious particles (virus) 5.infectious proteins (prions)
Pili/fimbrae are often ______.
lectins
What is the phagocytosis dodging capsule made of?
CHO!
How many times smaller is a bacterial cell compared to a human cell?
1000x
What is the size of the bacterial ribosome?
70s
What is LPS attached to on a Gram - bacterium? (BE SPECIFIC!)
the OUTER membrane!
What are the bacterial enzymes that ‘spot weld’ parts of the cell wall together?
transpeptidases
What are the enzymes that are constantly synthesizing and degrading peptidoglycan?
autolysins
What are the 2 initial targets of LPS?
1.Platelets/Fibrinogen 2. Macrophages
What is the chain events of LPS on the platelets/fibrinogon?
LPS–>platelets/fibrinogen–>D.I.C. (disseminated intravascular coagulation)–>Blocks blood flow
What are the 3 pathways of LPS acting on a Macrophage?
- LPS–>Macrophage–>TNF–>NO2 release/relax endothelial cells–>hypovolemic shock 2.LPS–>Mactophage–>PGE2–>activation of osteoclasts 3.LPS–>Macrophage–>releases collagenase–>destroys collagen fibers
What is the enzyme that splits peptidoglycan?
lysozyme
What is the only oxygen relationship that does not have SuperOxide Dismutase? Where is it found in the mouth?
Strict Anaerobes…subgingival
Does microaerophilic bacteria have SOD?CAT? Does it FERM?RESP? Where is it found in the mouth?
SOD:yes CAT:no Ferm:yes resp:no…supragingival
