L6 Flashcards

1
Q

antibodies are made by the cells of the ______ lineage

A

b lymphocyte

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2
Q

antibodies are produced by _____ that differentiate from _______

A

plasma cells
antigen specific b cells

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3
Q

what do b cells do in the bone marrow?

A

develop
also where they re-arrange their immunoglobulin genes
independent of antigen but does depend on special cells in the bone marrow - stromal cells

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4
Q

b cells then express their re-arranged immunoglobulin molecule on the membrane surface as ____

A

IgM class

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5
Q

when the IgM class cells mature, what do they do?

A

begin to express their re-arranged immunoglobulin molcule as an IgD class

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6
Q

CD19

A

classic surface protienses to identify b cells

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7
Q

when b cells encounter their specific antigen in lymph nodes, they _____ and eventually ____ into ____ and long lived ____

A

proliferate
differentiate
plasma cells
memory b cells

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8
Q
A
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