L5 Flashcards
movement of cells has 2 components
migration to a particular tissue / organ
movement within tissue / organ
how do you enhance the chances of rare antigen specific t and b cells of interacting with each other
have collections of t cells and immune cells in sites where infection is likely to happen
have cells circulate throughout body and have specialized sites of antigen capture here lymphocyte / antigen interactions are enabled
what are the primary lymphoid tissues?
where b and t cells develop - thymus and bone marrow
what are secondary lymphoid tissues
where lymphocytes migrate to - lymph nodes, spleen, MALT
efferent lymphatic vessel
drain away from lymph node
afferent lymphatic vessel
brings lymph to lymph nodes
sign to go revise lymphocyte activation process
woo
circulating lymphocytes encounter antigen in _____
peripheral lymphnodes
lymphocytes and lymph return to blood via the ____
thoracic duct
naive lymphocytes enter lymph nodes from ___
blood
go revise lymph node structure
woo
MALT
mucosal associated lymphoid tissues
GALT (gut associated lymphoid tissue) is important for what
making immunoglobulin A
m cell
specialized cell type - allows antigen to transit across epithelial barrier directly into peyer’s patch
the spleen has no ____
afferent lymphatics
