L5: The Stress Response Flashcards
Stress is an increase in _____ from and increase in ___
cortisol, ACTH
Walter Cannon
Fight-flight response (acute stress response)
Hans Seyle
Current defn of stress from observing biological responses of animals to noxious stimuli
Who won the nobel prize in 1950 for the physiology or medicine for the discoveries related to the hormones of the adrenal cortex?
Kendall, Reichstein, Hench
general adaptation syndrome
- Fight/flight
- Resistance reaction
- Exhaustion
who create the general adaptation syndrome
Hans Seyle
Eustress
Acute stress which is good
If the body’s adaptive mechanisms fail to meet challenges of stressors, then disease can result, known as “__”
Diseases of adaptation
General adaptation syndrome results from events associated with ____ stress
chronic (sustained cortisol levels) no neg feedback
What does chronic stress do to the HPA axis?
there is no neg feedback
sustained cortisol due to altered set point
recruitment of additonal HP pathways
If the resistance phase of the GAS fails to combar the stressor, the body moves to ______. WHich is associated with…
Stage 3. Exhaustion. Depletion of body stores, muscle wasting, impacts on immuity, etc
What is the goal of stage 2 of the GAS (resistance)?
Aimed at mobilizing glucose to continue fighting stressor
What are the 3 disorders related to chronic stress?
Psychological stress
PTSD Post traumatic stress disorder
Fibromyalgia
Physiological stress produces the same physiological profile as the ____ stress response and can lead to ____
acute, chronic
PTSD. Triggers? Symptoms? Treatment?
Violence, trauma, natural disaster
Flashbacks, nightmares, anxiety
Treatment- removal of the stressor
