L4: The Follicular Phase Flashcards
follicle recruitment is stimulated by _____
FSH
what determines follicle selection
follicle with most FSH recceptors
the dominant follicle requires an ______ surge for ovulation
LH
_______ inhibits the LH surge needed for ovulation
progesterone
- high progesterone causes insufficient GnRH/LH levels, inhibiting ovulation
a dominant follicle will become atretic when _____ is high, but will ovulate if ______ decays and _______ decreases
progesterone high –> atretic
corpus luteum decays and progesterone decreases –> ovulation
after luteolysis, the negative feedback of ___________ is removed
progesterone on HPG axis
after luteolysis, positive feedback of ________ occurs
estrogen on HPG axis
formation of ovulatory follicles and estradiol secretion occurs during what phase of estrus
proestrus
phase of estrus characterized by peak estrogen secretion
estrus
phase of estrus when CL forms and begins to secrete progesterone
metestrus
phase of estrus characterized by sustained luteal secretion of preogesterone, CL functions optimally
diestrus
what is Anestrus
period when cyclicity stops (during pregnancy, nursing, migration, stress, malnutrition, disease)
how/why do high levels of progesterone inhibit ovulation
high progesterone causes insufficient GnRH/LH levels
in most animals, ovulation timing corresponds to…?
the events in the estrous cycle
what happens in proestrus
formation of ovulatory follicles & estradiol secretion
when does proestrus happen
begins after CL regression and ends with the onset of estrus