L26: Forestomach fermentation digestion Flashcards

1
Q

T/F: Fermentation is slower than glandular digestion

A

T

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2
Q

give an example of a rapidly ferementable carbohydrate and a slowly fermentable one

A

sugar is fast
starch is medium
fiber is slow

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3
Q

what is needed for optimal fermentation

A
  1. pH, moisture, ion composition, redox-potential
  2. slow movement/long transit times facilitate reaction time
  3. specific motility patterns
  4. continuous removal of waste products; release of gases
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4
Q

what are the fermentation chambers

A
  • forestomach
  • sub-region in stomach (ex: non-glandular region in horses)
  • hindgut (colon & caecum)
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5
Q

end products of fermentation

A
  • VFA
  • microbial protein
  • gases
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6
Q

rumen microbes are _____, they coexist with the mammalian host for mutual benefit

A

mutualists

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7
Q

microbes initiate the degradation of ______ and detoxify ________

A

cellulose
allelochemicals

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8
Q

what happens if VFAs accumulate in the rumen

A

they lower the pH but the buffer (saliva) & removal from fermantation chamber helps maintain pH and avoid rumen acidification

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9
Q

T/F: microbes are substrate specific

A

T

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10
Q

what are the ways in which animals acqurie B12

A

diet (dogs,cats,pigs) and or by microbial production (ruminants)

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11
Q

dietary Cbl (Cobalamin) is bound to what 2 proteins

A

R-protein and intrinsic factor (IF) forming complexes

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12
Q

what cells secrete intrinsic factor (IF)

A

parietal

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13
Q

where is R protein digested

A

duodenum

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14
Q

where can Cbl be stored

A

liver and muscle

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15
Q

what can cause insufficient Cbl levels / B12

A
  • insufficient dietary Cbl
  • insufficient transport proteins caused by inflammation in stomach / SI which reduces R protein and/or IF production
  • reduced microbial production due to cobalt deficiency in the diet of ruminant
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16
Q

although ruminant microbes can produce B12, it has to be supplemented with ?

A

Cobalt

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17
Q

what is microbial yield

A

mass of microbial dry matter / mass of substrate

18
Q

what things affect microbial yield

A
  • temperature
  • pH
  • dilution rate of rumen fluid
  • C:N ratio in diet
19
Q

increased C:N ratio

A
  • enough energy but insufficient N
  • available E gets used by microbes for maintenance rather than growth
20
Q

decreased C:N ratio

A
  • ample N to support growth, but insufficient E for maintenance
  • available E is used for maintenance rather than growth
21
Q

increased or decreased glucose/protein ratios will ____ the microbial yield

22
Q

a matched glucose / protein ratio will ______ the microbial yield

23
Q

urea is formed in the ______ & is an an important source for _____

24
Q

where does hepatic urea come from

A
  • deamination of endogenous amino acids
  • nitrogen absorbed as ammonium in rumen
25
urea is mostly excreted via ?
urine but in ruminants, it can be recycled and partially returned to rumen via saliva
26
what does N flow to and from the rumen depend on
rumen ammonia concentration
27
effect of high nutritional protein concentration on blood urea
causes high blood urea; most of which is secreted in urine
28
how does low nutritional protein (w/ high CHO availability) affect the rumen
low rumen ammonia levels; stimulates nitrogen flow to rumen
29
the ______ portion of urea is used as the building block for the production of protein by rumen microbes
nitrogen
30
ammonia released from urea can go either of what 2 pathways
1. production of microbial protein 2. to the liver where it is detoxified and excreted in urine
31
in a ______ system, microbial growth is characterized by 4 phases: lag, log, stationary and decline
closed
32
why does microbial growth decline in a closed system
nutrients get exhausted and conditions (pH, Oxygen) become unfavorable
33
the rumen is mostly an _______ system, so microbial growth is continuous
open maintains cell population in exponential growth for long periods of time
34
what makes the rumen an open system
* feed input * gas release; VFAs absorbed * movement of rumen contents into omasum
35
what makes the rumen not an entirely open system
no - little oxygen
36
where in the GI tract is the IF-Cbl complex absorbed by endocytosis
ileum
37
what is dilution rate
large saliva volumes stabilize pH & provide fluid for dilution
38
what are the sources of nitrogen
* protein * urea * ammonia * nitrate
39
what is a major protein source for the host
microbial protein
40
does urea contain any E, minerals or vitamins
no
41
why might excess urea be bad
can overwhelm liver and cause toxicity