L34 Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

How long is the human gestation period from fertilization? What about from last menstrual cycle?

A

266 days from fertilization

280 days menstrual cycle
2 week different

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the 3 stage of prenatal ?

A

pre-embryonic 0 to 2 week
embryonic 2 to 8 week
fetal periods 9 to birth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Obstetricians commonly split the gestation period into what?

A

trimerster

they divide the 9-month period of gestation into three trimesters.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is the most critical stages of development

A

the first

trimester when embryonic and early fetal development is occurring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where specifically does fertilization occur?

A

The ampula of the Fallopian tube

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

morula [ 12-16 cells ] form at which day ?

A

3 day after fertilazation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what happen at day 4 ?

A

Early blastocyst is formed (Morula hollows out, fills with fluid, and “hatches” from the
zona pellucida ZP)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what happen at day 7 ?

A

implanting blastocyst that consist of inner mass[ embryoblast ] and outer mass [ trophoblast]
and the The fertilization membrane (zona pellucida) has degenerated and disappeared in order for the trophoblast to implant into the uterus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

during implantation the uterus is in which phase ?

A

secretory phase [ progesterone phase ]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Where exactly does the blastocyst implant?

A

On the posterior wall of the body of the uterus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what happen in day 8?

A

• The trophoblast at the embryonic pole differentiates into 2 layers:- Cytotrophoblast - Syncytiotrophoblast

cells of the inner cell mass (embryoblast) also differentiate into two layers: - Epiblast - Hypoblast
• At the same time, a small cavity appears in the epiblast called the amniotic cavity.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

true or false

amniotic cavity apeers in hypoblast

A

false it appere in the epiblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What happens at day 9?

A

Amniotic cavity expands
embryo is now a bilaminar disk (Epiblast and Hypoblast thicken)
Exocoloemic cavity (primary yolk sac) forms, and the Exocoelomic membrane, made from the Hypoblast, surrounds it (it is continuous with the Hypoblast)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What happens at days 11 and 12?

A

By the 11th- 12th day, the blastocyst is completely embedded in the endometrial stroma and uteroplacental circulation has been established.
- Extraembryonic mesoderm has been developed; soon large cavities formed in it then
become confluent to form extraembryonic coelom (chorionic cavity)………

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

the extraembryonic coelom [ chorionic cavity ] sorrounds?

A

the primary yolc sack and aminotic cavity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

The somatic layer with cyto and syncytiotrophoblast form a membrane called ?

A

chorion

17
Q

what is connecting stalk ?

A

the part where it does not cover by chrionic

18
Q

This separates the extraembryonic mesoderm into 2 layers?

A

somatic layer (lining the cytotrophoblast from outside) and splamthic layer (or visceral layer) which spurrounds the primary yolk sac

19
Q

etal blood vessels develop in the?

A

horionic villi which his sorrounded by intervillous space

​^ the chorionic villi which remains form the placenta

20
Q

what is the rule of 2?

A

A way to memorize in week 2 that

the trophoblast differentiates into 2 lyres [ cyto/syncytio - trophoblast ]
the embryoblast differentiates into 2 layers[ hypoblast / epiblast]
the extrareaByronic mesoderm splits into 2 layers [ somatic layer / splamthic layer]
there are 2 yolk sacs (prim and sec)
2 new cavities form[ aminotic and chronic]

21
Q

Becoming trilaminar and establishing body axes happen in which week ?

A

third week

22
Q

What is the first major event of week 3- and arguably the MOST important part of human development?

A

Gastrulation- meaning the formation of the gut
Formation of the 3 germ layers (Endo, meso, ecto)
Provides changes in the fate of the germ layers (differentiation) and start organogenesis
Establishing body axis (cranial- caudal left-right, etc)

23
Q

Formation of x defined for the first time the major body axes.
What is x, and what body axes are they?

A
The primitive streak
Cranial caudal (head-tail)
Dorsal ventral (back belly)
Medial lateral (left right)
24
Q

what is the longitudinal midline structure in the epiblast ear the caudal end of the bilaminar disk?

A

primative streak

25
Q

the X represent area where cells are leaving the Pramative streak and moving into the interior of the embryonic disc

A

primative groove

26
Q

Epiblast cells migrate through the primitive streak by movement called ?

A

ingression

27
Q

true or false
in week 2
PS moves through the midline of the Epiblast, (from caudal end - cranial) which makes the Epiblast cells migrate from the midline down towards the Hypoblast cells, and towards the lateral ends creating a primitive groove where they migrate.
The Hypoblast cells are displaced and the first layer is now the Endoderm 14 -15 days .
Afterwords, the Epiblast form another layer while migration creating the Mesoderrm
The Epiblast that remain, are now termed Ectoderm.

A

false

week 3

28
Q

Thus the X through the process of gastrulation becomes the source of all three germ layers
WHAT IS X

A

epiblast is the source of 3 germ layers

29
Q

What are the 2 membranes that have no mesoderm layers during the process of gastrulation?

A
The oropharyngeal membrane (cranial end and will become opening of mouth)
Cloacal membrane (caudal end and will become opening of anal canal)
30
Q

Notochord will form from the x and is on the y

A
x= primative node 
y= midline
31
Q

What is the function of the notochord?

A

Primordial longitudinal axis of the embryo and gives it some rigidity.
2- Signals for the development of CNS.

32
Q

What is the fate[ مصير] of the primitive streak?

A

The primitive streak diminishes in size and becomes an insignificant structure in the sacrococygeal regionof the embryo. Normally the primitive streak undergoes
degenerative changes and disappears by the end of week 4

33
Q

What is sacrococygeal teratoma?

A

A disease caused by the remanence of the primitive streak
Causes a tumor to be formed which contains tissues from all germ layers as the primitive streak is remaint of Epiblast (pluripotent)
Only occurs in the sacrococygeal region
Good prognosis

34
Q

In extreme cases, the deficiency in caudal development leads to fusion of the lower limb buds during early development resulting in a condition
called ?.

A

Sirenomelia

35
Q

What is caudal dysgenesis?

A

A group of syndromes that occur because of INSUFFICIENT mesoderm formation in the caudal region of the embryo.

36
Q

What are some characteristics of caudal dysgenesis?

A

Hypoplasia (poor formation of tissues and organs) and fusion of lower limbs
Anomalies of the lumber and sacral vertebrae
Agenesis of the kidney and urinary tract
Agenesis or internal genital organs EXCEPT GONADS
Imperforated anus
In EXTREME CASES - Sirenomelia (deficiency in caudal development leads to fusion of lower limb buds during early development