L23

Question 1

2 physiological concepts of adaptation

Answer 1

proteins continually turned over/recycled.
number and type of proteins driven by strain from stress

Question 2

how do we get more protein?

Answer 2

stress signals activate specific pathways which activate transcription factors that switch on/off genes to produce code for new proteins (mRNA). proteins made by ribosomes using this code.

Question 3

is signalling a prerequisute for proetin synthesis?

Answer 3

yes

Question 4

is protein synthesis ganrunteed?

Answer 4

no, also need amino acids to make protein. also the michinery (usable DNA, nuclei and ribosomes)

Question 5

What is the typical timeframe for mRNA response following an initial stress or stimulus

Answer 5

mRNA response peaks within hours after the stimulus, returning to baseline levels by approximately 24 hours. so we need to repeat an appropriate stress.

Question 6

how long does it take to see measurebale/functional protein synthesis

Answer 6

weeeks

Question 7

is there individual differences in protein synthesis ?

Answer 7

yes, huge

Question 8

when are proteins lost

Answer 8

over days to months.

Question 9

what four things does nature and extent of adaptation depend on

Answer 9

exercise parameters
personal (genes, age, clinical status)
diet - available of substare available
environment

Question 10

how does genes age and clinical status effect nature and extent of adaptation

Answer 10

genes - diff in 1000s genes (protein codes) and sex effect

ages - children less anabolic sex steriod hormone. old age blunted cell signalling

clinical - some diseases increase or decrease protein production.