L22- Hormonal Control Of Growth, Development And Reproduction

Question 1

Hormones involved in growth and their function

Answer 1

Insulin like growth factors- important during prenatal and post natal development
Growth hormone- important for post natal development
Thyroid hormone - important for prenatal brain development and post-natal development
Sex hormones- are important for growth and development

Question 2

Growth hormone is a ____ hormone secreted by ________in the ________

Answer 2

Peptide hormone secreted by somatotropic cells in anterior pituitary

Question 3

What does GH do

Answer 3

Main stimulus for somatic growth
Promotes synthesis and secretion of IGF1

Question 4

What are most effects of GH on growth mediated by

Answer 4

IGF1

Question 5

How does secretion of growth hormone occur

Answer 5

In discrete but irregular pulses, between pulses GH levels can be undetectable

Question 6

Secretion of GH is maximal when?

Answer 6

At night
In children
During puberty

Question 7

New bone tissue is added to what region

Answer 7

Epiphyseal growth plate

Question 8

what hormones stimulate bone growth

Answer 8

GH and IGF1

Question 9

GH stimulates differentiation of

Answer 9

Precursor cells in epiphyses plate into chondrocytes

Question 10

IGF1 acts in a ______manner to stimulate_______

Answer 10

Paracrine manner to stimulate chondrocyte cell division

Question 11

Other important effects of growth hormone / IGF1

Answer 11

Stimulates protein stnthesis in muscle/orher cell types (GH)
Increases levels of circulating energy sources (GH)
IGF1 powerful mitogen, promoting cell growth and division

Question 12

Thyroid hormone roles

Answer 12

Stimulate GH synthesis
Potentates effects of GH and IGF1
Promotes differentiation of chondrocytes

Question 13

Sex hormone synthesis is regulated by

Answer 13

Gonadotrophins (FSH/LH)

Question 14

I