L8- Design Of Pain Medication Flashcards
1
Q
What is the only NSAID which irreversibly inhibits Cox 1
A
Aspirin
2
Q
Antipyretic
A
Reduces fever
3
Q
What do NSAIDS reduce the level of
A
Prostaglandins (by blocking their synthesis from archidonic acid by COX enzymes
4
Q
Aspirin
A
- one of the salicylates
- irreversibly inhibits COX 1
- allows aspirin to inhibit platelet aggregation
5
Q
Propanoic acid derivatives
A
Ibuprofen, naproxen, flurbiprofen
6
Q
Ethanoic (acetic) acid derivatives
A
Diclofenac, aceclofenac
7
Q
Selective COX 2 inhibitors
A
Celecoxib, parecoxib, etoricoxib ( all have SO2)
8
Q
Which drugs strongly bind to both cox 1 and 2
A
Diclofenac and ibuprofen
9
Q
A
