L16: Shock Flashcards
What is the definition of shock
Failure of the circulation to deliver oxygenated blood to meet tissue requirements
What can a reduction of blood flow to the tissues lead to
Ishcaemia
What is ischaemia
Death of tissue cells
Which 2 vital organs cannot go without a blood supply
Brain
Heart
What happens when we have inadequate oxygen delivery describe the process involved
1) inadequate oxygen leads to anaerobic metabolism
2) lactic acid is produced which ends to metabolic acidosis and contributes to cell death
3) inadequate energy production leads to metabolic failure and contributes to cells death
How do we measure oxygen delivery to tissue in clinical practise
Lactate
Urinary output
What does lactate indicate
Anaerobic metabolism
What happens to urinary output in shock
Decreases
What 2 things determine how much oxygen is supplied to the tissue
How much o2 is dissolved in the blood
Cardiac output
In the blood where does oxygen bind to
Haemoglobin
How can we increase the oxygen supply to hb
Give the patient oxygen via a mask
What is the equation for cardiac output
CO= HR X SV
What is stroke volume determines by
Preload/venous return
Starlings law
What does the starlings law describe
As the EDV increases the SV increases
What is the afterload
The resistance the heart has to work against