L1 extracellular matrix Flashcards
what are the 4 types of tissues
Epithelial tissue, Connective tissue, Muscle tissue, Nervous tissue
What is the extracellular matrix (ECM)
A 3-D network made of extracellular molecules and mineral that provides structure and biochemical support to surrounding cells and tissues
what are the components of the ECM
proteins ( collagen, elastin), glycoproteins, minerals, hydroxyapatite
ground substance, fibre
what are the major cells in the ECM
fibrocytes (connective tissue proper) and chondrocytes (cartilage) osteocytes (bones)
what are the non-fibrous components of ECM
Glycosaminoglycans (GAGs) they are polysaccharide that trap water. Glycoproteins (oligosaccharide) and proteoglycans (polysaccharide): it gives the ground substance its structure and attach components to each other.
define ground substance
a gel like substance in the extracellular space that contains all the non-fibrous components of the ECM. It is composed of water and large organic molecules. It is involved in movement of tissue and provides lubrication
formula of connective tissue
ECM + Cells.
ECM = ground substance + fiber.
ground substance = proteoglycan + glycosaminoglycan + water + glycoprotein.
Fibers = collagen, elastic, reticular.
What are the fibers of the ECM and they properties
Collagen fiber (long, unbranched, provide strength, flexible, strong with tension) Reticular fiber (consist of collagen but are thinner and branched, form a flexible and strong structure for organs) Elastic (branched and stretchy)
what are the three type of connective tissue proper
areolar, adipose, reticular
what are the function of areolar connective tissues
hold organs in place, cushioning, attaches epithelial tissue to underlying tissue, allow cell movement.
what are the functions of adipose connective tissue
cushioning, stores energy, insulation
what are the function of reticular connective tissue
supporting skeleton for organs
