Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

AN4008 > L1 Andre > Flashcards

L1 Andre Flashcards

1
Q

fertilisation occurs in which region of Fallopian tube ?

A

ampullary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

whats cleavage ?

A

mitotic divisions resulting in increase of cells

cells = blastomeres

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

how is the inner cell mas formed ?

A

compaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

how many cells in the morula ?

A

16

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

inner cell mass will form ?

A

embryo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

outer cell mass will form ?

A

trophoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Implantation begins around day ?

finishes ?

A

day 6

day 9

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is zona pellucida

A

glycoprotein coat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

two components of trophoblast ?

A

cytotrophoblast (inner)

syncytiotrophoblast (outer)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

inner cell mass called ?

A

embryoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

embryoblast divides into ?

A

epiblast - columnar

hypoblast - cuboidal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

cavity in epiblast ?

A

amniotic cavity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

DAY 14

A

2 embryonic germ layers
2 cavities
2 components of trophoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

2 embryonic cavities ?

A

amniotic and yolk sac

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

symmetric cell divisions at 8 cell stage …

A

2 identical daughter cells divide to give trophoblast external cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

first asymmetric cell division ….

A

trophoblast still being formed
internal cells either become - bipotent cells or epiblasts
if they express FGF4 (epiblasts) pushing others to become hypoblast
if they express nanog = epiblast

17
Q

other waves of asymmetric division generates mostly ?

A

hypoblasts which have changes in adhesion and motility
during cavitation they migrate to inferior surface of inner cell mass to form thin epithelium
hypoblast express - SOX17 and GATA 6

18
Q

Cavitation is

A

formation of the blasocyst cavity

19
Q

Once the primitive endoderm (hypoblast) is formed …

A

cells expressing GATA6 and SOX17 that havent moved to inferior surface die

nanog expressing cells from epithelium superiorly

basal mem is formed between to layers

20
Q

Continued expression of FGF4 insures

A

continued expression of GATA6 and SOX17 for hypoblast differentiation

and inhibit nanog (epiblast factor)

21
Q

anterior visceral endoderm first secretes secretes ?

and function ?

A

DKK1 which inhibits Wnt

22
Q

Once fully formed the AVE secretes which 2 factors ?
effect ?
establishes ?

A

CER1 and LEFTY which inhibit nodal anteriorly
induction of cranial structures
establishes cranial end of embryo before gasturlation

23
Q

wnt 3 is expressed where ?

what does it induce ?

A

epiblast layer posteriorly which induces nodal posteriorly

24
Q

What effect does nodal have ?

A

stimulates the formation of the primitive node

25
Q

what day does gasturaltion begin ?

A

DAY 15

26
Q

What is gasturlation ?

A

process by which the definitive germ layers and axial orientation are established

27
Q

Where and how is the prim streak formed ?

A

the posterior midline of the epiblast

epiblast cells proliferate and migrate

28
Q

what does the prim streak establish?

A

L/R asymmetry

29
Q

The proliferation of epiclast causes the formation of depression ?

A

groove and pit

30
Q

Gasturaltion DAY 16 what happens ?

A

epithelial to meschemymal transition
Meschemymal to epithelial transition
population of the space between the difin ecto and endo to form defin mesoderm

31
Q

EMT is ?

A

epiblast around prim streak cells proliferate loose adherence, change shape and ingress

32
Q

MET is ?

A

2 waves of ingression as prim streak extends along midline - displacement of prim endoderm forms definitive embryonic endoderm

33
Q

what does remaining epiblast become ?

A

definitive embryonic ectoderm

34
Q

3 Types of mesoderm

A

Lateral plate mesoderm
Paraxial mesoderm
intermediate mesoderm

35
Q

How is prechordal plate formed ?

A

ingression through the cranial part of the prim node

36
Q

What is the prechordal plate

A

signalling centre for development of head and forebrain - head mesenchyme

37
Q

How is the notochord formed ?

A

ingression through prim node

NB signalling centre

AN4008 (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions