L-34 Flashcards
1
Q
Where are dendritic cells when the phagocytise antigens?
A
Major organs
2
Q
Where are dendritic cells when they present peptides on MHC to T cells?
A
Draining lymph nodes
3
Q
What to CD4 T cells do?
A
Help B cells make antibody
4
Q
What do CD8 T cells do?
A
become cytotoxic and kill virus infected cells and cancer cells
5
Q
How are MHC-I antigens processed?
A
Antigenic proteins are degraded to peptides in cytoplasm. these peptides are imported to the ER where peptide loading takes place
6
Q
How are MHC-II antigens processed?
A
Antigenic proteins are degraded in acidic phagolysosome. Peptide loading of MHC-II takes place in the phagolysosome
