KREBS CYCLE

Question 0

It is the final common pathway bec all biomolecules can enter

Answer 0

Krebs cycle

Question 1

Other term for krebs cycle

Answer 1

Citric acid cycle

tricarboxylic acid

Question 2

Where krebs cycle is located

Answer 2

Mitochondrial matrix

Question 3

Three enzymes used to produce acetyl coA

Answer 3

Pyruvate dehydrogenase complex

Question 4

During glycolysis,glucose is converted into

Answer 4

PYRUVATE

Question 5

Pyruvate undergoes removal of carboxyl grp

Answer 5

Oxidative decarboxylation

Question 6

Coenzymes used to produce acetyl coA

Answer 6

NAD
FAD
CoA SH
NADH
Lipoate
TPP thymine pyro phosphate

Question 7

Formation of NADH and FADH2 is catalyzed by

Answer 7

Dihydrolipoyl dehydrogenase

Question 8

E1

Answer 8

Pyruvate dehydrogenase

Question 9

E2

Answer 9

Dihydrolipoyl transacetylase

Question 10

E3

Answer 10

Dihydrolipoyl dehydrogenase

Question 11

Step 1:
Acetyl coA + _______ = Citrate
Enzyme used:

Answer 11

Oxaloacetate

Citrate synthase

Question 12

Step 2: Citrate ➡️ Isocitrate

What enzyme?

Answer 12

Aconitase

Question 13

This step shows you
rearrangement of func group or isomerization
reversible

Answer 13

Step 2: formation of isocitrate

Question 14

Step that shows generation of NADH

Answer 14

3 oxidation of isocitrate to a-KT & CO2
4 oxidation of a-KT to succinyl coA and CO2
8 oxidation of malate to oxaloacetate

Question 15

Irreversible
NAD ➡️ NADH
NADP ➡️ NADPH

Answer 15

3. Oxidation of a-KT & Co2

Question 16

Enzyme in step 3/ oxidation of a-KT & Co2

Answer 16

Isocitrate dehydrogenase

Question 17

Enzyme in formation of citrate

Step 1

Answer 17

Citrate synthase

Question 18

Enzyme in formation of isocitrate

Step 2

Answer 18

Aconitase

Question 19

Carries 3 mol

Answer 19

NADH

Question 20

Steps that shows:
Generation of NADH
Irreversible
Oxidation & decarboxylation

Answer 20

Step 3: oxidation of isocitrate to a-KT & Co2

Step 4: oxidation of a-KT to succinyl coA & Co2

Question 21

Enzyme in step 4/ oxidation of a-KT to succinyl coA & co2

Answer 21

A-ketoglutarate dehydrogenase complex

Question 22

High energy compound

Reactive product of the reaction

Answer 22

GDP

Question 23

Step 5:
Reactant:
Enzyme:
Product:
Production of....

Answer 23

Conversion of succinyl coA to succinate
Reactant: Succinyl coA 
Enzyme: succinyl coA synthetase or thiokinase
Product: succinate
GDP*

Question 24

This step demonstrates SUBSTRATE LEVEL OF PHOSPHORYLATION

Answer 24

Step 5

Conversion of succinyl coA to succinate

Question 25

Charac of step 5–

Forms atp/ gtp without entering electron transport chain

Answer 25

Substrate level of phosphorylation

Question 26

Step 6:
Enzyme:
Formation of ___

Answer 26

Oxidation of succinate to fumarate
Succinate DEhydrogenase
FADH2

Question 27

Step 7:

Enzyme:

Answer 27

Hydration of fumarate to malate

Enzyme: fumarase

Question 28

Step 8:

Emzyme:

Answer 28

Oxidation of malate to oxaloacetate

Malate dehydrogenase

Question 29

Products formed in krebs cycle

Answer 29

3 NADH
GDP
FADH2

Question 30

of atp..
NADH
GDP
FADH2

Answer 30

N-3
F-2
G-1

Question 31

How many atp based on 1 mol of acetyl coa

Answer 31

12 atp

Question 32

Enzyme in substrate level of phosphorylation

Answer 32

Succinyl coA synthetase

Question 33

Irreversible steps and enzymes..

Answer 33

1. Formation of citrate - citrate synthase
2. Oxidation of isocitrate to a-KT & co2
3. Oxidation of a- KT to succinate & co2 - a ketoglutarate dehydrogenase complex

Question 34

Reversible reaction

Serves as replenishment for Krebs cycle

Answer 34

Anaplerotic reaction

Question 35

Product formed in anaplerotic rxn

Answer 35

Oxaloacetate

Question 36

Rate limiting enzymes that catalyze rate limiting steps

Answer 36

Citrate synthetase
Isocitrate dehydrogenase
A ketoglutarate dehydrogenase complex

Question 37

step ➡️ FADH2

Answer 37

Step 6

Oxidation of succinate to fumarate

Question 38

Step ➡️ GDP

Answer 38

Step 5

Conversion of succinyl coA to succinate