ELECTRON TRANSPORT CHAIN Flashcards
Features of ETC
Made up of 4 complexes
Electron transfer
Redox reaction
Proton pump
Transferring the e from one complex to another
ETC
4 protein complexes
Nadh dh
Succinate dh
Cyt bc1 complex
Cyt oxidase
Electron carriers from krebs cycle
Nadh
Fadh2
Heme protein electron carrier
Cytochrome
Not a protein electron carrier
Ubiquinone
What type of cytochrome is present in complex III
Cyt bc1 complex
Complex III – What are the absorbants in Cyt Bc1 complex
B562
B566
Enzyme that catalyze complex III
Ubiquinone: cytochrome oxidoreductase
Types of cytochrome in complex III based on wavelength
Heme A
heme B
Heme C
Impt of complexes
For electron transport and proton pump gradient
Cytochrome used in Complex IV
Cyt aa3
Enzyme that catalyze complex IV
Cytochrome oxidase
Only cytochrome that contains COPPER in its structure
Complex IV
It has a ligand or free attachment for oxygen
Complex IV
Only complex that has NO PROTON PUMP
Complex II
Other terms for complex V
ATPase synthase
Mitochondrial ATPase
F1 F0 ATPase
Complex where actual ATP synthesis happens
Complex V
Complex V: contains enzymes that catalyze ATP
Catalytic portion or F1
Complex V: pathway..
Proton channel or F0
Prevents flow of electrons
Inhibitors
Function of inhibitors
Electron transport
Uncoupling agent
If present, there is no proton pump formed. Instead hydrogen ions are released as HEAT
Uncoupling agent
It will bind to the stalk of ATP
Oligomycin
It inhibits ATP synthase and blocks complex V
Oligomycin
