GLYCOGENOLYSIS Flashcards
Enzyme that breaks a 1,4 linkages
Catalyzes phosphorolysis
Glycogen phosphorylase
Branched polymer of glucose (a 1,6)
Stored in liver and skeletal muscle
Glycogen
2 forms of glycogen phosphorylase:
- active when phosphorylated
- active when dephosphorylated
A
B
Cofactor of glycogen phosphorylase
PLP (vit B3)
Pyrodoxal phosphate
Debranching enzymes (removes branching points)
4:4 glucosyl transferase
a 1,6 glucosidase
Endpoint of glycogenolysis in skeletal muscle:
Glucose 6-phosphate
Enzyme:
G6P ➡️ G1P
Phosphoglucomutase
High energy phosphate combined with glucose
UDP Glucose
It has the ability to transfer glucose unit to the primer of glycogenesis
UDP glucose
Primer where you attached glucose units to lengthen chain of glycogen via a 1,4 linkage
Glycogenin
Forms a 1,4 linkage
Glycogen synthase
Enzymes that break a portion of the linear the transfer it to CARBON 6
Branching enzymes
Branching enzymes:
Amylo (1-4) to (1-6) transglycosylase
Glycosyl (4-6) transferase
End product of glycogenesis
Glycogen