CORI CYCLE Flashcards
Capable of undergoing anaerobic glycolysis
Cori cycle
Lactic acid cycle occurs in the LIVER & muscle
Cori cycle
Cori cyle -
Glucose alanine cycle -
Cori- lactate
Glu- alanine amino acid
Functions of Pentose phosphate pathway
Catabolism of pentose sugars from the diet
Source of NADPH
Source of D-ribose
Synthesis of less common 4C and 7C sugars
Route for interconversion of pentose & hexoses
Served as cofactor of fatty acid,cholesterol,nucleotide, neurotransmitter
Nadph
Antioxidant that uses NADPH to be activated
Glutathione
Pentose phosphate pathway occurs in
Cytosol
2 phases of PPP
Reversible:
Irreversible:
Non oxidative rxns
Irre-oxidative rxns
Oxidative reactions:
When NADPH is generated, _ is produced
Ribulose 5 phosphate ➡️ ribose 5 phosphate
Enzyme that is seen in glycolysis, gluconeogenesis, pentose phosphate pathway
Glucose 6-phosphate dehydrogenase
Enzyme used to form d-ribulose 5 phosphate
6-phosphogluconate dehydrogenase
Diff of NADH & NADPH
Nadh- carry atp
Nadph- cofactor only dont carry atp
Features of oxidative reactions
Single direction Irreversible Generation of NADPH Ribulose 5-phosphate > ribose 5 phosphate Can go to nucleic acid synthesis Source of D-ribose
Interconversion
Form intermediate of glycolysis
Reversible
Non oxidative reaction
Enzyme that shows interconversion (epimerization)
Ribose 5 phosphate epimerase