Klebsiella pneumoniae Flashcards

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1
Q

What type of pili are necessary for adhesion to urinary tract epithelial cells?

A

Type 1

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2
Q

What ype of pili are necessary for adhesion to respiratory tract epithelial cells?

A

Type 3

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3
Q

How does this pathogen induce a watery diarrhea?

A

Secrete an enterotoxin that is similar to ST and LT

(increase cAMP/cGMP) to mess up the ion concentration and have water leave the cells

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4
Q

Why is aerobactin important for Klebsiella?

A

It sequesters iron, preventing the host from getting it

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5
Q

Why is the capsule important for Klebsiella?

A

It is the most important thing for the virulence
There are lots of macrophages in the respiratory tract. This capsule makes it difficult for the macrophages to both recognize and engulf Klebsiella.

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