Kach: Psychotherapeutic Agents

Question 1

The main difference between bipolar 1 & 2

Answer 1

Severity of manic episodes, which are more severe in bipolar I and less severe in bipolar II:

Question 2

Cyclothymia is ….

Answer 2

Similar to bipolar 1 but less severe

Question 3

Antipsychotics maybe used for

Hyperactivity
Combativeness
Behavior problem in kids

Chlorpromazine 1st generation

Is also used …

Answer 3

Tetanus
NV
Iractable Hiccups

Question 4

IM antipsychotics are weaker or stronger

Answer 4

Stronger 4 or 5X

Question 5

Low Potency antipsychotics Dosage

High Potency Dosage

Answer 5

Low 2 - 25

High up to 100 Thiolidazine

Question 6

Antipsychotics
Why use woth caution in Glaucoma, Peptic Ulcers, Urinary/ Intestinal blockage

Answer 6

Anticholinergic effects

Question 7

Blocking of dopamine leads to increased levels of _____ and results in gyenoclymastia

Answer 7

Prolactin

Question 8

Why should patients taking antipsychotics have a baseline & periódic ECGs.

Answer 8

QT prolongation & fatal cardiac arythmias

Question 9

DM is more likely with typical or atypical antipsychotics

Answer 9

Atypical 2nd gen

Question 10

Chlorpromazine, fluphenazine, Prochlorperazine, promethazine, thiolidazine

Can do this to urine output

Answer 10

Turn it pink to reddish brown

Question 11

Clozapine REMS

Normal ANC New patient

BEN Population
* who are the BEN population
*special consideration

Answer 11

Normal ANC New patient
ANC >1500

BEN Population
ANC >1000
Africa, Middle East, India
*special consideration
2 baseline ANC readings before treatment

Question 12

Clozapine REM

ANC monitoring

First 6 months

6 - 12 months

> 12 months

Answer 12

First 6 months: Weekly

6 - 12 months: Every 2 weeks

> 12 months: Monthly

Question 13

Clozapine REM

If Treatment is interrupted:

<30 days
>30 days

Answer 13

<30 days: Continue Monitoring as before

> 30 days: Treat as new patient

Question 14

Clozapine REM

MILD NEUTROPENIA 1000- 1499

General population- ANC monitoring

BEN population Monitoring

Answer 14

General population- ANC monitoring
3 x Weekly until ANC >1500

BEN population Monitoring
Normal findings, normal monitoring

Question 15

Clozapine REM

Moderate Neutropenia 500 - 999

Normal Population
ANC monitoring

BEN population

Answer 15

Normal Population

Rec Hematology consultation
Interrupt treatment for sus Clozapine neutropenia
Resume treatment ANC >1000

Monitoring: Daily until ANC > 1000 then
3x weekly until ANC >1500
ONCE >1500 Measure ANC weekly 4 weeks then return patient to normal

BEN population

Recommend Hematology consulate
Continue treatment

3X Weekly until ANC >1000
Once 1000 CHECK ANC weekly 4 weeks

Question 16

CLOZAPINE REM
Severe Neuroleptia <500

General population….
Monitoring ….

BEN population…..
Monitoring….

Answer 16

Gen pop
Hematology consultation
Stop treatment

Monitoring Daily until ANC >1000 then
3x weekly until ANC >1500
If patient is Rechallenged start under New Patient “Normal Range “ >1500

BEN population
Hematology consultation
Stop treatment

Monitoring

Daily until ANC >500
If patient is rechallenged resume treatment as new patient under Normal Range monitor ANC >1000