Chapter 14 Book Depression Flashcards
SE: Agitation, insomnia, headache, NV, Sexual Dysfunction, hyponatremia
Class
SSRI
This SNRI inhibits reuptake of norepinephrine more than 5 HT.
SE: OH, constipation, sweating, increased HR, palpitations, difficulty urinating, decreased appetite, Sexual Dysfunction
Levomilnacipran
This SNRI is approved for GAD.
SE: N, xerostomia, insomnia, somnolencia, constipation, reduce appetite, fatigue, sweating, blurred vision
Duloxetine
Venlafaxine SNRI is popular choice after SSRI.
WARNING
Monitor BP esp at high levels
Nefazodone, Trazodone, Vilazodone, Vortioxetine
This class
Serotonin Antagonist and Reuptake Inhibitor
Bupropion NDRI smoking stopper at low dose (poor man’s coccaine)
Has this Contradiction
Seizures
Use caution in older adults with Cardiac Problems, Elevated intraocular pressure, urinary retention, Hyperthyroidism, seizures, liver & Kidney dysfunction. Lethal in OD
Tricyclic antidepressants
Amitriptyline
Amoxapine
Doxepin
Imipramine
Nortriptyline
Disruptive mood dysregulation is….
Why was the diagnosis invented….
Constant & severe irritability and anger Ages 6 - 18
To prevent them from being labeled bipolar and taking wrong meds.
They grow outta it and become either depressed or Anxious
Persistent depressive disorder/ Formerly Dysrhthmias
Is this level ____ of depression that last 2 years Most days of the week
In addition have atleast 2 of the following: appetite problems, insomnia/ hypersomia, low energy, poor Self-Esteem, difficulty thinking hopelessness
Low level
Premenstrual Dysphoric Disorder
Can best be relieved by..
Which SSRIs
Regular exercise, carbohydrate rich foods & sleep, acupuncture, light therapy, relaxation.
Fluoxetine, Sertraline, Controlled release Paroxetine
Major depressive disorder is characterized by 5 or more symptoms of depression lasting atleast how long….
2 weeks
Can a person whose son just died last month be considered clinically depressed
Yes
Now the Bereavement exclusion is removed from the DSM
Leading cause of disability worldwide.
Most common psychological illness in USA
Depression
Anxiety
Women are more depressed than men.
Biracial people are the most depressed race
T & T
Two main neurotransmitters involved in mood are..
5 HT & norepinephrine
Serotonin or Norepinephrine
Attention
Behavior
Sleep
Appetite
Sex drive
Impulse control
Irritability
Norepinephrine
Attention
Behavior
Serotonin
Sleep
Appetite
Sex drive
Impulse control
Irritability
Hyperactivity of HPA & increased urine cortisol & elevated corticotrophin-releasing hormones
Are associated with depression?
T
C-reactive protein & interleukin-6 may play a role in depression. What do they both do?
Inflammation