Juvenile Idiopathic Arthritis Flashcards

1
Q

What is juvenile idiopathic arthritis?

A

Systemic inflammatory disorders of the under 16yo

Cause disability and blindness

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2
Q

How common is juvenile idiopathic arthritis?

A

1 in 1000

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3
Q

What are the criteria for diagnosis of juvenile idiopathic arthritis?

A

<16 years
>6 week duration
Joint swelling, or painful, limited motion with warmth

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4
Q

what are the major subtypes of juvenile idiopathic arthritis?

A

Pauciarticular (50%)
Polyarticular (25)
Systemic onset

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5
Q

Which form of juvenile idiopathic arthritis is more common in males?

A

Enthesitis related

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6
Q

How does type 1 juvenile idiopathic arthritis typically present?

A
Lower limb joints (knee ++)
Asymptomatic
Iris inflammation
Limp 
Girls:boys 8:1
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7
Q

How does type 2 juvenile idiopathic arthritis typically present?

A

Girls:boys 1:7
LL joints, asymmetric
Dactylitis
Rapid damage with back involvement

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8
Q

What is pauciarticular JIA?

A

4 or less joints involved

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9
Q

What is polyarticular JIA?

A

5 or more joints

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10
Q

How does RF-ve Polyarticular JIA present?

A
Fever, malaise
Hepato-splenomegaly 
Anaemia
Growth abnormalities
Stiffness all over body and symmetric
Girls++
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11
Q

How does RF+ve Polyarticular JIA present?

A
Fever, malaise, weight loss
Anaemia
Nodules 
Other autoimmune diseases
Girls++
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12
Q

How does Systemic onset JIA present?

A
Starts early and disappears after 5 years
Hepatosplenomegaly
Abdominal pain 
Legs, wrists, spine, TMJ
Polyserositis
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13
Q

Uveitis is most commonly associated with which form of JIA?

A

Oligo JIA

ANA+ve

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14
Q

What complications are associated with Uveitis?

A

Posterior synechiae
Cataract
Band keratopathy

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15
Q

How is Uveitis screened for in JIA?

A

Screened in ALL JIA

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16
Q

How is Uveitis treated in JIA?

A

Steroids
Methotrexate
Ciclosporin
Anti-TNF

17
Q

What is the mangement of JIA?

A
Pain killers
NSAIDs
Methotrexate
Anti-TNF
Anti-IL-1,6
Systemic steroids
Physiotherapy/OT
18
Q

How does JIA affect growth?

A

Localised growth failure
Shortening limbs/digits
Short stature
Delayed puberty