Juvenile Idiopathic Arthritis Flashcards
What is juvenile idiopathic arthritis?
Systemic inflammatory disorders of the under 16yo
Cause disability and blindness
How common is juvenile idiopathic arthritis?
1 in 1000
What are the criteria for diagnosis of juvenile idiopathic arthritis?
<16 years
>6 week duration
Joint swelling, or painful, limited motion with warmth
what are the major subtypes of juvenile idiopathic arthritis?
Pauciarticular (50%)
Polyarticular (25)
Systemic onset
Which form of juvenile idiopathic arthritis is more common in males?
Enthesitis related
How does type 1 juvenile idiopathic arthritis typically present?
Lower limb joints (knee ++) Asymptomatic Iris inflammation Limp Girls:boys 8:1
How does type 2 juvenile idiopathic arthritis typically present?
Girls:boys 1:7
LL joints, asymmetric
Dactylitis
Rapid damage with back involvement
What is pauciarticular JIA?
4 or less joints involved
What is polyarticular JIA?
5 or more joints
How does RF-ve Polyarticular JIA present?
Fever, malaise Hepato-splenomegaly Anaemia Growth abnormalities Stiffness all over body and symmetric Girls++
How does RF+ve Polyarticular JIA present?
Fever, malaise, weight loss Anaemia Nodules Other autoimmune diseases Girls++
How does Systemic onset JIA present?
Starts early and disappears after 5 years Hepatosplenomegaly Abdominal pain Legs, wrists, spine, TMJ Polyserositis
Uveitis is most commonly associated with which form of JIA?
Oligo JIA
ANA+ve
What complications are associated with Uveitis?
Posterior synechiae
Cataract
Band keratopathy
How is Uveitis screened for in JIA?
Screened in ALL JIA
How is Uveitis treated in JIA?
Steroids
Methotrexate
Ciclosporin
Anti-TNF
What is the mangement of JIA?
Pain killers NSAIDs Methotrexate Anti-TNF Anti-IL-1,6 Systemic steroids Physiotherapy/OT
How does JIA affect growth?
Localised growth failure
Shortening limbs/digits
Short stature
Delayed puberty
