Jun LE6 Flashcards
1
Q
- Which of the following accurately describes spermiogenesis?
a. Occurs before puberty
b. Involves stem cells, meiosis, and spermatogenesis
c. Involves cytodifferentiation of early spermatids
d. Occurs in diploid cells
e. Results in the formation of primary spermatocytes
A
c. Involves cytodifferentiation of early spermatids
2
Q
- A man with a pituitary gonadotrophic tumor causing hyposecre-tion of FSH is most likely to exhibit which condition?
a. No symptoms, since he has no ovarian follicles
b. Loss of libido (sex drive)
c. Low serum testosterone levels
d. Low sperm count
e. Prostatic hypertrophy
A
d. Low sperm count
3
Q
- Interstitial cells of Leydig have an important function in male gamete production. Because of this function, which of the following organelles is abundant within these cells?
a. Lysosomes
b. Smooth endoplasmic reticulum
c. Peroxisomes
d. Polyribosomes
e. Golgi complexes
A
b. Smooth endoplasmic reticulum
4
Q
- While studying a germ cell line developed from a patient’s testicular biopsy, the researcher notes that colchicine-treated cells blocked in metaphase have 46 chromosomes. From which of the following regions of the male genital tract would you expect these cells to have originated?
a. Within the rete testis
b. At the basal lamina of the seminiferous tubule
c. In the middle region of the germinal epithelium
d. Within the adluminal compartment of the seminiferous tubule
e. Within the straight tubules
A
b. At the basal lamina of the seminiferous tubule
5
Q
- Which of the following organs is normally characterized by the accumulation of corpora amylacea with increasing age?
a. Prostate
b. Seminal vesicles
c. Bulbourethral (Cowper) glands
d. Epididymis
e. Ductus (vas) deferens
A
a. Prostate
6
Q
- Within the male reproductive tract, stereocilia project from cells lining which of the following regions?
a. Rete testis
b. Seminiferous tubules
c. Ampulla of the ductus deferens
d. Epididymis
e. Penile urethra
A
d. Epididymis
7
Q
- As sperm pass through the male genital ducts, proteins and low-molecular-weight products are added from several sources producing semen. Which of the following provides a nutritive, fructose-rich secretion?
a. Interstitial cells of Leydig
b. Bulbourethral (Cowper) glands
c. Prostate gland
d. Epididymis
e. Seminal vesicles
A
e. Seminal vesicles
8
Q
- A 20-year-old man contracts cholera during a long tour of military duty in a remote, completely undeveloped region. After a 5-day period of severe diarrhea and treatment, he gradually recovers and slowly returns to work. He is married 3 years later but after a few years of trying to conceive a child, semen analysis reveals that his sperm are few in number and malformed, and blood tests show a high titer of antibodies against sperm antigens. The causative agent of cholera, Vibrio cholera, secretes a toxin that interferes with tight (occluding) junctions. What cells in the gonad are the likely target of this toxin in the male reproductive system?
a. Spermatogonia
b. Sertoli cells
c. Myoid cells
d. Interstitial cells of Leydig
e. Differentiating spermatozoa
A
b. Sertoli cells
9
Q
- A 29-year-old man presents with testicular pain and a burning sensation during urination. Tests reveal the presence of Neisseria gonorrhea and penicillin is prescribed. Gonorrhea often produces acute or chronic inflammation of the testes and frequently involves the channels that connect the testis to the epididymis. What is the name of these channels?
a. The mediastinum testis
b. The rete testis
c. Efferent ductules
d. The straight tubules (tubuli recti)
e. The seminiferous tubules
A
c. Efferent ductules
10
Q
- A 39-year-old man undergoing an extensive series of tests for infertility is found to have a genetic mutation preventing formation of a functional synaptonemal complex during meiosis, causing almost complete failure of sperm formation. Which cells would be directly affected by this mutation?
a. Primary spermatocytes
b. Spermatogonia
c. Secondary spermatocytes
d. Spermatids
e. Cells undergoing spermiogenesis
A
a. Primary spermatocytes
11
Q
- Which stage of ovarian follicle development is characterized by an initial period of follicular fluid accumulation?
a. Graafian follicle
b. Mature follicle
c. Primordial follicle
d. Oocyte
e. Secondary follicle
A
e. Secondary follicle
12
Q
- Which of the following is characteristic of granulosa lutein cells?
a. Are a minor cell type in the corpus luteum
b. Derive from the theca interna
c. Contain abundant rough endoplasmic reticulum
d. Are small and dark-staining
e. Secrete progesterone
A
e. Secrete progesterone
13
Q
- Which of the following hormones is primarily responsible for inducing ovulation?
a. Relaxin
b. LH
c. Progesterone
d. FSH
e. Estrogen
A
b. LH
14
Q
- Which feature is characteristic of the corpora albicans but not of atretic follicles?
a. May contain degenerating granulosa cells floating in remnants of follicular fluid
b. Resemble large collagenous scars
c. Eventually removed by macrophages and replaced by stroma
d. Are remnants of follicles that degenerate before maturation
e. May contain degenerating oocytes
A
b. Resemble large collagenous scars
15
Q
- Endometrial glands are typically most fully developed and filled with product during which day(s) or phase of a woman’s menstrual cycle?
a. Menstrual phase
b. Days 1-4
c. The day ovulation occurs
d. Proliferative phase
e. Days 15-28
A
e. Days 15-28