jaundice

Question 1

Common parasite causing Jaundice

Answer 1

Clonorchis Sinensis (Chinese liver fluke)

Question 2

Classic presentation for Primary Biliary Cirrhosis

Answer 2

Female 30-65yr (female 10x more likely)
jaundice (conjugated)
xanthomas
high serum cholesterol
fatigue
cirrhosis

PBC: inflammation, granulomatous destruction of intrahepatic bile ducts (autoimmune)

Question 3

Antibody associated with Primary Biliary Cirrhosis

Answer 3

AMA (Anti-Mitocondrial Antibody)

Question 4

Differential diagnosis of Dubin-Johnson and Rotor syndrome

Answer 4

both are hereditary disorders causing conjugated hyperbilirubinemias

Dubin-Johnson has BLACK PIGMENTATION of the liver