gastric 5 Flashcards
0
Q
Hyperplastic polyps occur in
A
left colon
serrated appearance (saw tooth)
benign
1
Q
Ischemic colitis most likely to occur at what location?
A
Splenic flexure, very last thing fed by the SMA
results in postprandial pain (after meal)
2
Q
What is Adenoma Carcinoma sequence
A
progression of adenomatous polyp into carcinoma
APC (adenomatous polyposis choli gene) mutation of both genes
KRAS mutation
P53 mutation (can become carcinoma)
Increased cyclooxygenase expression
3
Q
Risk factors for adenomatous polyps to become carcinoma
A
size >2cm sessile growth (not like a mushroom, more like a bulge)
4
Q
Gene mutation leading to Famial Autosomal Polyposis
A
APC mutation on chromosome 5
100% of cancer
5
Q
Peutz Jeghers syndrome
what is it
presentation
A
Hamartomatous polyps throughout GI
hyperpigmentation of lips, oral mucosa, genital skin
