Cardiac 1 Flashcards
Hallmark of Stable angina on EKG
ST segment depression
Stable Angina only when atherosclerosis is ____ (number)
> 70% stenosis (from atherosclerosis) of coronary arteries
Definition of Unstable Angina
Chest pain at rest
due to rupture of atherosclerotic plaque with thrombosis and incomplete occlusion of coronary artery
Prinzemetal Angina is
Vasospasm of coronary artery
episodes of chest pain unrelated to exertion
Possible causes of Myocardial Infarction
rupture of atherosclerotic plaque with thrombosis and COMPLETE occlusion leading to necrosis of myocytes
Prinzemetal vasospasm for greater than 20 minutes
Embolism
Vasculitis (inflammation > thrombus)
Marker for MI
Troponin I
rises 2-4hr after infarction
peaks @ 24hrs
returns to normal by 7-10 days
What marker is useful for detecting re-infarction a couple days after initial episode?
CK-MB
rises 4-6hrs after infarction
but returns to normal by 72hrs unlike Troponin I
Treatments for MI
ASA/heparin supplemental O2 Nitrates (reduces preload) Beta blocker (prevents arrhythmia) ACE inhibitor (prevents water retention)
Fibrinolysis or angioplasty can cause Contraction Band necrosis. What is it?
Sudden repurfusion introduces Ca++ which causes contraction of necrotic tissue. Histologically, it’s bands in myocytes
Symptoms of pulmonary congestion
Edema Dyspnea Orthopnea Paroxymal nocturnal dyspnea Orthopnea Crackles
What causes Heart Failure Cells
Left sided heart failure leads to excess blood in pulmonary circulation. Rupture of capillaries leads to blood in alveoli air sacks. Macrophages consume that blood and will become HEMOSIDERIN LADEN MACROPHAGES aka Heart Failure Cells
Cor Pulmonale is…
Due to
Right sided heart failure due to pulmonary blood vessels constricting due to hypoxia in the lungs.
Jugular Vein Distention due to
Right side heart failure
Cardiac congestion symptoms
JVD
Hepatosplenomegaly (painful)
Cardiac Cirrhosis
Pitting Edema
Most common type of Atrial Septal Defect
Ostium Secundum